boswellic acid

09/01/2021 - "GR-mediated anti-inflammation of α-boswellic acid: Insights from in vitro and in silico studies."
01/01/2020 - "Thus, our studies support the application of Piper longum with Boswellic acid as a novel therapeutic avenue in diseases associated with inflammation."
02/01/2012 - "To evaluate the efficacy of boswellic acid against monosodium urate crystal-induced inflammation in mice. "
01/01/2023 - "Allosteric Activation of 15-Lipoxygenase-1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation."
09/01/2021 - "Hence, glucocorticoid receptor (GR)-mediated anti-inflammation of α-boswellic acid was investigated in this work. "

01/01/2015 - "The antinflammatory natural product boswellic acid is effective against cancer at least in part by inducing tumor cell apoptosis. "
10/01/2016 - "Considering this perspective, the present review highlights the established studies related to the anti-cancer potential of boswellic acid against different cancer types. "
01/21/2015 - "This study explored the anti-cancer agent and boswellic acid analog BA145 as an inducer of autophagy and angiogenesis-mediated cytoprotection of tumor cells. "
06/01/2013 - "The present study relates to the induction of apoptosis thereof cytotoxicity and anti-cancer activity displayed by semi-synthetic analog of Boswellic acid i.e. "
07/01/2012 - "Induction of apoptosis of the semi-synthetic derivative of β-boswellic acid-POBA in vitro was analyzed using a battery of human cancer cell lines followed by cell cycle phase distribution, further validated by DNA fragmentation, and was found to cause mitochondrial membrane potential loss with ultrastructural changes, as observed by electron microscopy studies and expression study using PARP cleavage, as well as validated by in vivo anti-tumor activity. "

03/01/2018 - "The results of this study showed that boswellic acid suppresses the growth of HCT-116 colon cancer cells. "
03/01/2018 - "In this study we report the anticancer activity of boswellic acid against human colon cancer cells via induction of apoptosis, cell cycle arrest and inhibition of cell migration and PI3K/AKT signalling pathway. "
08/01/2006 - "2. In the present study, we showed that acetyl-keto-beta-boswellic acid (AKBA) inhibited cellular growth in several colon cancer cell lines. "
01/01/2021 - "The Editors of JBUON issue an Expression of Concern to 'Boswellic acid exerts potent anticancer effects in HCT-116 human colon cancer cells mediated via induction of apoptosis, cell cycle arrest, cell migration inhibition and inhibition of PI3K/AKT signalling pathway', by Dan Wang, Shuke Ge, Jichang Bai, Yongwei Song, JBUON 2018;23(2):340-345; PMID:29745074. "
01/01/2021 - "Boswellic acid exerts potent anticancer effects in HCT-116 human colon cancer cells mediated via the induction of apoptosis, cell cycle arrest, cell migration inhibition and inhibition of PI3K/AKT signalling pathway"

11/21/2022 - "This study aimed to compare the effect of Boswellic acid derivatives on the viability, apoptosis, and epigenomic profiling of breast cancer. "
11/21/2022 - "Comparative study of the cytotoxicity, apoptotic, and epigenetic effects of Boswellic acid derivatives on breast cancer."
01/01/2016 - "The combination of boswellic acid, betaine, and myoinositol has been demonstrated to be effective in the treatment of breast pain and radiologically and histologically confirmed benign breast mass and in the reduction of breast density, one of the pivotal risk factors for the development of breast cancer, without any side effects. "
01/01/2013 - "In the present study, we aimed to validate these findings by using docking protocols and explicate the possible mechanism of action for a dataset of nine phytochemicals namely boswellic acid, 1-caffeoylquinic acid, ellagic acid, emodin, genistein, guggulsterone, quercetin, resveratrol, and sylibinin from different plants against the nuclear factor- kappaB (NF-κB) precursor protein p105, an important transcription factor reported to be overexpressed in breast cancer. "

01/01/2021 - "Alzheimer's disease improved through the activity of mitochondrial chain complexes and their gene expression in rats by boswellic acid."
04/01/2022 - "The exact mechanism of beta boswellic acid action in Alzheimer's disease pathogenesis remains unclear. "
01/01/2020 - "On the other hand, boswellic acid derivatives have also been shown to be involved in Alzheimer's disease. "
01/01/2021 - "In conclusion; the boswellic acid improved the antioxidant and mitochondrial complexes in Alzheimer's disease."
04/01/2022 - "In the current study, the protective effect of beta boswellic acid on streptozotocin-induced sporadic Alzheimer's disease was surveyed. "