2-hydroxyglutaryl-CoA dehydratase

from Acidaminococcus fermentans; catalyzes dehydration of (R)-2-hydroxyglutarate in the presence of acetyl-CoA and glutaconate CoA transferase; forms glutaconyl-CoA, an iron-sulfur enzyme.

Also Known As:

2-hydroxyglutaryl-coenzyme A dehydratase

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Lyases: 637
    - Carbon-Oxygen Lyases
      - Hydro-Lyases: 266
        2-hydroxyglutaryl-CoA dehydratase: 1

Experts

1.	Buckel, Wolfgang: 1 article (05/2011)
2.	Kahnt, Jörg: 1 article (05/2011)
3.	Parthasarathy, Anutthaman: 1 article (05/2011)
4.	Pierik, Antonio J: 1 article (05/2011)
5.	Zelder, Oskar: 1 article (05/2011)

Related Diseases

1.	Dehydration (Water Stress) 05/03/2011 - "2-Hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum, the key enzyme of this pathway and a potential radical enzyme, catalyzes the reversible dehydration of (R)-2-hydroxyglutaryl-CoA to (E)-glutaconyl-CoA. "

Related Drugs and Biologics

1.	Enzymes
2.	glutaconyl-coenzyme A