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5- methylsulfonylamino- 6- phenoxy- 1- indanone

structure given in first source

Also Known As:

CGP 28237; CGP-28237; ZK 34228; ZK-34228; Methanesulfonamide, N-(2,3-dihydro-1-oxo-6-phenoxy-1H-inden-5-yl)-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Indenes: 4
        Indans: 7
        5-methylsulfonylamino-6-phenoxy-1-indanone: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Indenes: 4
    - Indans: 7
      - 5-methylsulfonylamino-6-phenoxy-1-indanone: 2

Related Diseases

1.	Embolism (Embolus) 01/01/1987 - "Although CGP 28237 is not a cyclooxygenase inhibitor in bovine seminal vesicle microsomes, it inhibits prostaglandin synthesis in zymosan-stimulated murine macrophages (IC50 approximately 3 X 10(-6) mol/l) and protects rabbits against arachidonic acid-induced lung embolism with 10 mg/kg p.o. "
2.	Experimental Arthritis 01/01/1987 - "CGP 28237 exhibits potent anti-inflammatory activity in developing and established adjuvant arthritis in rats (ED40 approximately 0.5 mg/kg p.o.) and good activity in carrageenin oedema (ED40 approximately 3 mg/kg p.o.). "
3.	Arthritis (Polyarthritis) 01/01/1988 - "6-Sulfanilamidoindazole arthritis in rats: influence of the new anti-inflammatory agent CGP 28237 and of the immunomodulating compound HWA 486 on degree of arthritis and on acute phase reaction."
4.	Acute-Phase Reaction 01/01/1988 - "6-Sulfanilamidoindazole arthritis in rats: influence of the new anti-inflammatory agent CGP 28237 and of the immunomodulating compound HWA 486 on degree of arthritis and on acute phase reaction."

Related Drugs and Biologics

1.	Cyclooxygenase Inhibitors
2.	Arachidonic Acid (Vitamin F)
3.	Zymosan
4.	Prostaglandins
5.	Carrageenan
6.	Anti-Inflammatory Agents (Anti-Inflammatories)
7.	Leflunomide (Arava)
8.	6-sulfanilamidoindazole