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1- (6- (2,4- dichlorophenyl)- 3- pyridazinyl)- 4- piperidinol

Also Known As:

3-(4-hydroxypiperidyl)-6-(2,4-dichlorophenyl)pyridazine; SR 41378; SR-41378

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridazines: 11
    - 1-(6-(2,4-dichlorophenyl)-3-pyridazinyl)-4-piperidinol: 2

Related Diseases

1.

Seizures (Absence Seizure)

01/01/1992 - "On the contrary, SR 41378 exhibited an extreme efficacy in 7-day-old rat pups, where even the 1.25 mg/kg dose significantly decreased the incidence and severity of seizures. "
01/01/1992 - "Both drugs suppressed minimal as well as major seizures in all age groups studied in a dose-dependent manner, SR 41378 being approximately four times more potent than CM 40907. "
11/01/1986 - "Two amino-phenyl-pyridazine derivatives, SR 41378 and CM 40907, have been reported to antagonize seizures in mice, rats and Papio papio baboons with comparable potencies. "
01/01/1992 - "The action of two potential anticonvulsants, CM 40907 (10-50 mg/kg i.p.) and SR 41378 (1.25-20 mg/kg i.p.) against metrazol-induced seizures was studied in rats 7, 12, 18 and 25 days old. "

Related Drugs and Biologics

1.	CM 40907
2.	Pentylenetetrazole (Metrazol)
3.	Anticonvulsants (Antiepileptic Drugs)
4.	pyridazine