suppressin

calf-thymus hormone with 17-19 amino acid residues; used to treat histiocytosis-X; MW: 1700 daltons;

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

1.	Pituitary Neoplasms (Pituitary Adenoma) 01/05/1990 - "Finally, metabolic labeling studies using a rat pituitary tumor cell line, GH3, showed that suppressin was synthesized de novo and secreted by these cells." 07/01/1993 - "Suppressin (SPN) is a novel polypeptide that is synthesized and secreted by normal rat pituitary cells and a rat pituitary tumor cell line, GH3. "
2.	Histiocytosis 01/01/1988 - "Response to treatment with daily intramuscularly administered crude calf thymic extract (Suppressin) in 11 patients with Langerhan's histiocytosis (L.H.) is reported. "
3.	Thromboembolism 10/04/1969 - "Puerperal thromboembolism and suppressin of lactation by oestrogen."
4.	Neoplasms (Cancer) 11/01/2001 - "Suppressin (SPN), a novel inhibitor of the entry into the cell cycle, has properties of a tumor suppressor gene; however, its role in the development and progression of a human malignancy is not studied. "
5.	Adenocarcinoma 11/01/2001 - "Altered subcellular localization of suppressin, a novel inhibitor of cell-cycle entry, is an independent prognostic factor in colorectal adenocarcinomas."

1.	Peptides (Polypeptides)