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calretinin

MW 29kDa; from chick retina; expressed principally in neurons; CR-22k is an alternatively spliced form of calretinin

Also Known As:

CALB2 protein, human; Calb2 protein, mouse; Calb2 protein, rat; calb2 protein, zebrafish; calbindin 2; calbindin 2 protein, mouse; calbindin 2 protein, rat; calbindin 2, (calretinin) protein, zebrafish; calbindin 2, 29kDa (calretinin) protein, human; calretinin protein, human; calretinin protein, mouse; calretinin protein, rat; calretinin protein, zebrafish; calretinin-22k

Networked: 684 relevant articles (18 outcomes, 71 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 90489
  - Carrier Proteins: 11456
    - Calcium-Binding Proteins: 268
      - Vitamin D-Dependent Calcium-Binding Protein: 10
        calretinin: 684

Experts

1.	Ordóñez, Nelson G: 9 articles (07/2014 - 08/2003)
2.	Schwaller, Beat: 8 articles (11/2015 - 11/2004)
3.	Young, Robert H: 8 articles (10/2015 - 02/2005)
4.	McCluggage, W Glenn: 7 articles (10/2015 - 02/2005)
5.	Oliva, Esther: 7 articles (10/2015 - 01/2005)
6.	Blum, Walter: 4 articles (11/2015 - 07/2013)
7.	Zhang, Paul J: 4 articles (01/2014 - 03/2003)
8.	Miettinen, Markku: 4 articles (09/2012 - 02/2003)
9.	Fukunaga, Masaharu: 4 articles (01/2012 - 09/2004)
10.	Deavers, Michael T: 4 articles (01/2012 - 04/2003)

Related Diseases

1.	Mesothelioma 10/01/1998 - "Among these, calretinin generated a great deal of interest, but the number of studies evaluating the practical use of calretinin immunostaining in the diagnosis of mesothelioma is limited, and the study results are controversial. " 01/01/2015 - "The mechanistic understanding of the function of calretinin and its putative implication in signaling pathways in normal mesothelial cells may help understanding its role during the processes that lead to mesothelioma formation and could possibly open new avenues for mesothelioma therapy, either by directly targeting calretinin expression or indirectly by targeting calretinin-mediated downstream signaling." 01/01/2015 - "Diagnostic accuracy of calretinin for malignant mesothelioma in serous effusions: a meta-analysis." 04/15/2014 - "We studied the expression of MIF and CD74 together with calretinin in specimens of malignant pleural mesothelioma (MPM), correlating their expression levels with clinico-pathologic parameters, in particular overall survival (OS). " 01/01/2014 - "Immunocytochemistry showed positivity for calretinin and WT-1.A diagnosis of right submandibular salivary gland involvement from mesothelioma was established, allowing an adequate treatment. "
2.	Adenocarcinoma 04/01/2009 - "The aim of our study was to determine the value of a panel that consisted of one epithelial marker (MOC-31) and two mesothelial markers (D2-40 and calretinin) for distinguishing between reactive mesothelial cells (RMCs) and adenocarcinomas (ACs) in effusion fluids. " 01/01/2012 - "For lung adenocarcinomas, we found Ber-EP4, CEA and TTF1 positivity, and calretinin, D2-40 and CK5/6 negativity. " 11/01/2011 - "Fifty-three primary breast adenocarcinomas were analysed for immunohistochemical expression of calretinin. " 01/01/2011 - "Among the adenocarcinoma cases, 49 (98%) were calretinin negative but Ber-EP4 positive. " 01/01/2008 - "All cases of the metastatic adenocarcinoma were negative for calretinin and D2-40. "
3.	Carcinoma (Carcinomatosis) 12/01/2013 - "The objectives of this study were to (1) further delineate the expression of calretinin in grade 3 breast carcinomas in the context of molecular subtypes and (2) identify the impact of calretinin expression on overall and disease-free survival. " 11/01/2011 - "This study was aimed at evaluating the frequency of calretinin expression in primary breast carcinomas, and assessing the characteristics of the calretinin-positive tumours. " 05/01/2015 - "Pseudomesotheliomatous small-cell neuroendocrine carcinoma of the lung with calretinin expression." 11/01/2011 - "Positive calretinin and CK5/6 are not specific, and may be seen in both mesothelial cells and basal-like breast carcinomas. " 11/01/2011 - "CK14 staining was more specifically associated with triple-negative tumours than CK5/6. Calretinin positivity was statistically associated with basal-like carcinomas. "
4.	Neoplasms (Cancer) 11/01/1997 - "Calretinin is a very useful marker for positive identification of normal and tumor mesothelial cells in serous effusions." 02/01/2005 - "Although CD99 and calretinin are often expressed in these tumors, they are much less specific and not as helpful in the differential diagnosis. " 06/01/2015 - "Immunohistochemistry studies of LATS1, LATS2, Pax8, and calretinin were performed on normal ovary, fallopian tube, normal endometrium, and ovarian tumor sections. " 07/01/2008 - "The aim of this study was to determine whether immunohistochemistry for calretinin allows identification of cutaneous adnexal tumors with follicular differentiation towards cells of the outer root sheath. " 07/01/2008 - "[Immunohistochemical study of calretinin in normal hair follicles and tumors with follicular differentiation]."
5.	Hirschsprung Disease (Hirschsprung's Disease) 04/01/2013 - "To evaluate the efficacy of calretinin immunostaining in diagnosing Hirschsprung's disease (HD). " 07/01/2015 - "This study was undertaken to ascertain 1) clinical profile; 2) mode of presentation; 3) to evaluate the role of Calretinin immunostain in the diagnosis of Hirschsprung's Disease. " 05/01/2013 - "A study of calretinin in Hirschsprung pathology, particularly in total colonic aganglionosis." 06/01/2012 - "This study was designed to assess the utility of calretinin immunohistochemistry in the diagnosis of Hirschsprung's disease. " 07/01/2015 - "Hirschsprung's Disease in Neonates with Special Reference to Calretinin Immunohistochemistry."

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