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burchellin

isolated from Piper hancei Maxim; structure given in first source

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - burchellin: 7

Experts

1.	Suzuki, Takashi: 2 articles (01/2020 - 01/2018)
2.	Azambuja, P: 2 articles (09/2004 - 09/2001)
3.	Garcia, E S: 2 articles (09/2004 - 09/2001)
4.	Asami, Satoru: 1 article (01/2018)
5.	Kurita, Masahiro: 1 article (01/2018)
6.	Ono, Shinichi: 1 article (01/2018)
7.	Takada, Tomomi: 1 article (01/2018)
8.	Uchiyama, Taketo: 1 article (01/2018)
9.	Wakabayashi, Noriko: 1 article (01/2018)
10.	Barbosa-Filho, J M: 1 article (03/2010)

Related Diseases

1.	Infections 09/15/2004 - "cruzi infection, burchellin significantly reduces the gut infection, whereas NDGA does not. " 09/01/2001 - "In a treatment of Trypanosoma cruzi-infected fourth instars, burchellin significantly reduced the population density of the established infection in the rectum at 5 and 10 days after feeding. " 03/01/1999 - "cruzi infection, although burchellin significantly reduced the gut infection, neither compound could abolish the infection entirely within the subsequent 15 days." 03/01/1999 - "When the insect larvae were pretreated with burchellin or NDGA at 20 days before the infection with T. "
2.	Chagas Disease (American Trypanosomiasis) 01/01/2008 - "The neolignan, burchellin, a natural compound that reduces urine excretion in larvae of the bloodsucking bug, Rhodnius prolixus, a vector of Chagas' disease, is rapidly degraded in the hemolymph of the insect. " 03/01/2010 - "Due to our results, burchellin and licarin A need to be further analysed to observe if they may be used as alternative blood additive prophylaxis against Chagas disease, since it has been established that blood transfusion is an important mechanism in the transmission process."
3.	Neuroblastoma 01/01/2018 - "We found that one of the burchellin derivatives (compound 4) exerted cytotoxicity against the neuroblastoma cell lines. " 01/01/2018 - "We examined the antitumor effects of five burchellin derivatives against human neuroblastoma cell lines. " 01/01/2018 - "Antitumor Effect of Burchellin Derivatives Against Neuroblastoma." 01/01/2020 - "We extracted many compounds from natural plants (Angelica keiskei, Alpinia officiarum, Lycaria puchury-major, Brassica rapa) or synthesized cyclophane pyridine, indirubin derivatives, vitamin K3 derivatives, burchellin derivatives, and GANT61, and examined their effects on apoptosis, cell differentiation, and cell cycle in neuroblastoma and ESFT cell lines compared with normal cells. "

Related Drugs and Biologics

1.	Vitamin K 3 (Menadione)
2.	Lignans
3.	Cyclophanes
4.	GANT 61
5.	licarin A
6.	indirubin
7.	pyridine

Related Therapies and Procedures

1.	Blood Transfusion (Blood Transfusions)