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ORF 17583
structure given in first source
Also Known As:
BL 6217; BL-6217; N-(4-(methylamino)-1-oxo-1,2,5-thiadiazol-3-yl)-2-((5-(dimethylaminomethyl)-2-furyl)methylthio)ethylamine; ORF-17583
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Furans: 85
Ranitidine: 2334
ORF 17583: 1
Related Diseases
1.
Gastric Fistula
08/01/1987 - "
ORF 17583, a histamine H2-receptor antagonist, inhibited gastric acid secretion in pylorus-ligated rats (ED50 = 4.9 mg/kg intraduodenal; 3.4 mg/kg p.o.; and 0.21 mg/kg i.p.) and in total gastric fistula or Heidenhain pouch dogs stimulated by betazole (ED50 = 0.12 mg/kg p.o.
"
08/01/1987 - "
Oral antisecretory potency of ORF 17583 in gastric fistula dogs was 31 times greater than cimetidine, 3.7 times greater than ranitidine and equal to that of omeprazole and famotidine.
"
Related Drugs and Biologics
1.
Famotidine (Pepcid)
2.
Ranitidine (Zantac)
3.
Omeprazole (Prilosec)
4.
Histamine (Histamine Dihydrochloride)
5.
Cimetidine (Biomet)
6.
Betazole (Histalog)