kahweol

12/01/2014 - "In this study, we investigated whether kahweol could show anti-cancer effects on oral squamous cell lines (OSCCs), HN22 and HSC4. "
11/01/2018 - "Furthermore, we found that blocking Akt signaling through kahweol treatment significantly reduced FASN expression and subsequently suppressed cell proliferation in HER2-overexpressing cancer cells. "
09/01/2016 - "However, the mechanism responsible for the anti-cancer effects of kahweol is not fully understood. "
12/01/2014 - "Taken together, results from these findings suggest that kahweol may be a potential anti-cancer drug candidate to induce apoptotic cell death through downregulation of Sp1 in OSCCs."
12/01/2014 - "However, the molecular mechanisms underlying the anti-cancer activity of kahweol have not yet established. "

07/04/2018 - "Kahweol Ameliorates the Liver Inflammation through the Inhibition of NF-κB and STAT3 Activation in Primary Kupffer Cells and Primary Hepatocytes."
07/04/2018 - "In this study, we examined whether kahweol exhibits a protective effect by inhibiting liver inflammation in primary Kupffer cells and primary hepatocytes cultures as well as their co-cultures. "
10/01/2023 - "Pretreatment with kahweol by gavage for 5 days significantly alleviates lung pathological injury, inflammation, and oxidative stress, accompanied by shifting the dynamic process of mitochondria from fission to fusion, enhancing mitophagy, and activating AMPK. "
07/04/2018 - "These results suggest that kahweol might be a novel potent agent to treat liver inflammation induced by LPS."
07/04/2018 - "However, to date, the effect of kahweol on liver inflammation remains unknown. "

05/01/2017 - "The present study was performed to investigate the molecular mechanism by which kahweol stimulates ATF3 expression and apoptosis in human colorectal cancer cells. "
05/01/2017 - "The results suggest that kahweol induces apoptosis through ATF3-mediated pathway in human colorectal cancer cells."
05/01/2017 - "Kahweol increased apoptosis in human colorectal cancer cells. "
09/01/2016 - "Kahweol inhibited markedly the proliferation of human colorectal cancer cell lines such as HCT116, SW480. "
09/01/2016 - "The main aim of this investigation was to determine the effect of kahweol on cell proliferation and the possible mechanisms in human colorectal cancer cells. "

12/06/2020 - "Kahweol Ameliorates Cisplatin-Induced Acute Kidney Injury through Pleiotropic Effects in Mice."

09/27/2019 - "We found that kahweol treatments significantly reduced secondary brain injury and improved neurobehavioral outcomes in TBI mice. "