N,N',N''-triacetylfusarinine C

from Mycelia sterilia; ferric ionophore for this organism; structure given in first source

Also Known As:

triacetylfusarinine C; Iron, ((N2-acetyl-N5-hydroxy-N5-(5-hydroxy-3-methyl-1-oxo-2-pentenyl)-L-ornithine trimol. lactonato)(3-))-, stereoisomer

Networked: 12 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Iron Compounds: 87
  - Ferric Compounds: 6
    - N,N',N''-triacetylfusarinine C: 12
Organic Chemicals: 133
- Amines: 4871
  - Hydroxylamines: 16
    - Hydroxamic Acids: 239
      - N,N',N''-triacetylfusarinine C: 12
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Hydroxamic Acids: 239
      - N,N',N''-triacetylfusarinine C: 12

Experts

1.	Haas, Hubertus: 7 articles (12/2020 - 02/2012)
2.	Orasch, Thomas: 4 articles (09/2020 - 10/2017)
3.	Decristoforo, Clemens: 3 articles (12/2020 - 12/2019)
4.	Pfister, Joachim: 3 articles (12/2020 - 12/2019)
5.	Petrik, Milos: 3 articles (05/2020 - 01/2018)
6.	Gsaller, Fabio: 2 articles (12/2020 - 01/2019)
7.	Novy, Zbynek: 2 articles (12/2019 - 01/2018)
8.	Faserl, Klaus: 2 articles (01/2019 - 10/2017)
9.	Hoenigl, Martin: 2 articles (01/2019 - 10/2017)
10.	Lindner, Herbert: 2 articles (01/2019 - 10/2017)

Related Diseases

1.	Aspergillosis 12/01/2022 - "fumigatus , triacetylfusarinine C (TAFC), has been successfully detected by mass spectrometry in serum, BALF and urine of patients with invasive aspergillosis, with promising sensitivities and specificities in single-centre studies. " 09/01/2020 - "Rapid detection of the aspergillosis biomarker triacetylfusarinine C using interference-enhanced Raman spectroscopy." 01/01/2019 - "Triacetylfusarinine C: A urine biomarker for diagnosis of invasive aspergillosis." 11/12/2022 - "The BALF samples from 22 patients with proven or probable aspergillosis were assayed for human pentraxin 3 (Ptx3), fungal ferricrocin (Fc), and triacetylfusarinine C (TafC) in a retrospective study. " 09/01/2020 - "Triacetylfusarinine C (TAFC) is a siderophore produced by certain fungal species and might serve as a highly useful biomarker for the fast diagnosis of invasive aspergillosis. "
2.	Infections 05/29/2020 - "The proof of principle was the imaging of pulmonary Aspergillus fumigatus infection using [68Ga]Ga-triacetylfusarinine C. " 10/26/2022 - "fumigatus, which reveals that its substrate, triacetylfusarinine C, is the most important siderophore during infection. "
3.	Coinfection 09/06/2021 - "The invasive coinfection was detected by monitoring the fungal triacetylfusarinine C and ferricrocin siderophore levels and the bacterial metabolites pyoverdin E, pyochelin, and 2-heptyl-4-quinolone, studied in the urine, endotracheal aspirate, or breath condensate. "
4.	Invasive Pulmonary Aspergillosis 10/01/2017 - "Bronchoalveolar lavage triacetylfusarinine C (TAFC) determination for diagnosis of invasive pulmonary aspergillosis in patients with hematological malignancies."
5.	Hematologic Neoplasms (Hematological Malignancy) 10/01/2017 - "Bronchoalveolar lavage triacetylfusarinine C (TAFC) determination for diagnosis of invasive pulmonary aspergillosis in patients with hematological malignancies."

Related Drugs and Biologics

1.	Siderophores
2.	Peptides (Polypeptides)
3.	Amino Acids
4.	ferricrocin
5.	Biomarkers (Surrogate Marker)
6.	Iron
7.	2-heptyl-4-quinolone
8.	PTX3 protein
9.	pyoverdin
10.	pyochelin