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2'-deoxytubercidin

structure given in first source

Also Known As:

2'-deoxy-7-deazaadenosine; 7-deaza-2'-deoxyadenosine

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Tubercidin: 42
        2'-deoxytubercidin: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Tubercidin: 42
      - 2'-deoxytubercidin: 2
  - Ribonucleosides: 49
    - Tubercidin: 42
      - 2'-deoxytubercidin: 2

Experts

1.	Nelson, J Arly: 1 article (04/2007)
2.	Pan, Bih Fang: 1 article (04/2007)

Related Diseases

1.	Hypersensitivity (Allergy) 12/01/1989 - "Since these thymidines are rendered incapable of participating in Hoogsteen base pairs by the incorporation of 7-deaza-2'-deoxyadenosine, we conclude that this unusual base-pairing scheme is not the cause of the observed hypersensitivity to osmium tetroxide and that it therefore results from a large local unwinding of the DNA in the presence of the antibiotic. "
2.	Renal Cell Carcinoma (Grawitz Tumor) 04/01/2007 - "We previously reported (UroOncology 1:165, 2001) cross-resistance and collateral-sensitivity to 2-chlorodeoxyadenosine (CldAdo) and fludarabine (FaraA), respectively, in a human renal cell carcinoma selected for resistance to 2'-deoxytubercidin (Caki-dTub). "

Related Drugs and Biologics

1.	Cladribine
2.	Osmium Tetroxide
3.	DNA (Deoxyribonucleic Acid)
4.	Anti-Bacterial Agents (Antibiotics)
5.	fludarabine