HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

1-methylxanthine

urinary metabolite of caffeine

Networked: 12 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Xanthines: 123
    - 1-methylxanthine: 12
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Xanthines: 123
        1-methylxanthine: 12

Experts

1.	Jeong, Seong-Yun: 2 articles (05/2009 - 02/2009)
2.	Park, Heon Joo: 2 articles (05/2009 - 02/2009)
3.	Cai, Jinliang: 1 article (06/2022)
4.	Cen, Manqiu: 1 article (06/2022)
5.	Chen, Xinzhen: 1 article (06/2022)
6.	Fu, Xihang: 1 article (06/2022)
7.	Li, Huiru: 1 article (06/2022)
8.	Song, Lingling: 1 article (06/2022)
9.	Wu, Jing: 1 article (06/2022)
10.	Yao, Ting: 1 article (06/2022)

Related Diseases

1.	Hyperthermia 05/08/2009 - "In this study, we evaluated the efficacy of 1-methylxanthine (1-MTX), a caffeine metabolite as a radiosensitizer and the in vivo effectiveness of the temperature-sensitive liposomal 1-methylxanthine (tsl-MTX) in combination with ionizing radiation and regional hyperthermia. "
2.	Neoplasms (Cancer) 02/01/2009 - "1-Methylxanthine enhances the radiosensitivity of tumor cells." 02/01/2009 - "To determine the efficacy of a caffeine derivative 1-methylxanthine (1-MTX) in increasing radiosensitivity of cancer cells and elucidate the underlying mechanisms in vitro. "
3.	Melanoma (Melanoma, Malignant) 05/01/2022 - "The present study revealed that treatment with the melanogenesis stimulators 3-isobutyl 1-methylxanthine (IBMX) and α-melanocyte-stimulating hormone (α-MSH) significantly inhibited VM in MNT-1 human pigmented melanoma cells. "
4.	Acquired Immunodeficiency Syndrome (AIDS) 12/01/1996 - "Twenty-one cases of advanced AIDS patients (CD4 < 200/microliter) were involved in this study, all Europeans except one black, were acetylate phenotyped via analysis of caffeine metabolites, named 5-Acetylamino-6-formylamino-3-methyluracil, 1-Methylxanthine and 5-Acetylamino-6-amino-3-methyluracil, in human urine collected 2 hours after a cup of caffeine-spiked coffee and their plasma/lymphocyte glutathione concentrations were determined, by high performance liquid chromatographic method. "
5.	Cognitive Dysfunction 07/01/2023 - "We observed that 1-methylxanthine, 3-methylxanthine, 7-methylxanthine, 1,3-dimethylxanthine, 1,7-dimethylxanthine, and 3,7-dimethylxanthine levels were significantly and inversely associated with cognitive decline. "

Related Drugs and Biologics

1.	Caffeine (No Doz)
2.	1-Methyl-3-isobutylxanthine (1 Methyl 3 isobutylxanthine)
3.	Coffee
4.	5- acetylamino- 6- formylamino- 3- methyluracil
5.	Melanocyte-Stimulating Hormones (MSH)
6.	Glutathione (Reduced Glutathione)
7.	5-acetylamino-6-amino-3-methyluracil
8.	Theophylline (Theon)
9.	3-methylxanthine
10.	1,3-dimethyluric acid