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adefovir

inhibitor of African swine fever virus
Also Known As:
9-(2-phosphonomethoxyethyl)adenine; 9-(2-phosphonylmethoxyethyl)adenine; 9-PMEA
Networked: 729 relevant articles (122 outcomes, 108 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Ahn, Sang Hoon: 12 articles (01/2020 - 11/2007)
2. Park, Jun Yong: 10 articles (01/2020 - 01/2009)
3. Byun, Kwan Soo: 9 articles (01/2019 - 08/2007)
4. Kwon, So Young: 9 articles (01/2019 - 07/2008)
5. Lim, Young-Suk: 9 articles (01/2019 - 06/2006)
6. Han, Kwang-Hyub: 9 articles (01/2017 - 11/2007)
7. Kim, Do Young: 9 articles (01/2017 - 01/2009)
8. Kim, Yoon Jun: 8 articles (01/2020 - 07/2011)
9. Lee, Han Chu: 8 articles (01/2019 - 06/2006)
10. Yim, Hyung Joon: 8 articles (10/2015 - 12/2009)

Related Diseases

1. Chronic Hepatitis B
2. Infections
3. Hepatitis B
4. Fibrosis (Cirrhosis)
5. Retroviridae Infections (Infection, Retrovirus)
07/01/1991 - "Single-dose administration of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP) in the prophylaxis of retrovirus infection in vivo."
01/13/1994 - "Foremost among the acyclic nucleoside phosphonates currently pursued for their potential in the treatment of herpes and retrovirus infections are (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) and 9-(2-phosphonylmethoxyethyl)adenine (PMEA). "
10/01/2003 - "Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections."
01/01/1997 - "The acyclic nucleoside phosphonates [HPMPC (cidofovir), PMEA (adefovir) and PMPA] have proved to the effective in vitro (cell culture systems) and in vivo (animal models, clinical studies) against a wide variety of DNA virus and retrovirus infections: i.e., HPMPC against herpesvirus (herpes simplex virus type 1 and 2, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus, human herpesvirus types 6, 7, and 18), polyoma-, papilloma-, adeno-, and poxvirus (vaccinia virus, molluscum contagiosum virus) infections; PMEA against herpesvirus, hepadnavirus (human hepatitis B virus) and retrovirus (human immunodeficiency virus type 1 and 2, simian immunodeficiency virus, and feline immunodeficiency virus) infections; and PMPA against both hepadna- and retrovirus infections."
10/01/2003 - "The acyclic nucleoside phosphonates HPMPC (cidofovir), PMEA (adefovir), and PMPA (tenofovir) have proved to be effective in vitro (cell culture systems) and in vivo (animal models and clinical studies) against a wide variety of DNA virus and retrovirus infections: cidofovir against herpesvirus (herpes simplex virus types 1 and 2 varicella-zoster virus, cytomegalovirus [CMV], Epstein-Barr virus, and human herpesviruses 6, 7, and 8), polyomavirus, papillomavirus, adenovirus, and poxvirus (variola virus, cowpox virus, vaccinia virus, molluscum contagiosum virus, and orf virus) infections; adefovir against herpesvirus, hepadnavirus (human hepatitis B virus), and retrovirus (human immunodeficiency virus types 1 [HIV-1] and 2 [HIV-2], simian immunodeficiency virus, and feline immunodeficiency virus) infections; and tenofovir against both hepadnavirus and retrovirus infections. "

Related Drugs and Biologics

1. Lamivudine (Epivir)
2. entecavir
3. Tenofovir (Viread)
4. Antiviral Agents (Antivirals)
5. lipoarabinomannan (LAM)
6. Nucleosides
7. Hepatitis B e Antigens
8. Telbivudine
9. adefovir dipivoxil (Hepsera)
10. Cidofovir (Vistide)

Related Therapies and Procedures

1. Therapeutics
2. Liver Transplantation
3. Drug Therapy (Chemotherapy)
4. Salvage Therapy
5. Hematopoietic Stem Cell Transplantation