methyl-3-methoxy-4-hydroxystyryl ketone

structure given in first source; RN given refers to cpd without isomeric designation

Also Known As:

4-(4-hydroxy-3-methoxyphenyl)-3-buten-2-one; 4-hydroxy-3-methoxybenzalacetone; MMHSK; dehydrozingerol; dehydrozingerone; methyl-3-methoxy-4-hydroxystyryl ketone, (E)-iosmer; vanillidene acetone

Networked: 18 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Styrenes: 6
        methyl-3-methoxy-4-hydroxystyryl ketone: 18

Experts

1.	Gourishetti, Karthik: 2 articles (11/2021 - 10/2020)
2.	Bastow, Kenneth F: 2 articles (09/2007 - 10/2006)
3.	Itokawa, Hideji: 2 articles (09/2007 - 10/2006)
4.	Lee, Kuo-Hsiung: 2 articles (09/2007 - 10/2006)
5.	Nakagawa-Goto, Kyoko: 2 articles (09/2007 - 10/2006)
6.	Tatsuzaki, Jin: 2 articles (09/2007 - 10/2006)
7.	Baliga, Manjeshwar Shrinath: 1 article (11/2021)
8.	Kudva, Avinash Kundadka: 1 article (11/2021)
9.	Mudgal, Jayesh: 1 article (11/2021)
10.	Prasad, Krishna: 1 article (11/2021)

Related Diseases

1.	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 11/01/2021 - "Dehydrozingerone ameliorates Lipopolysaccharide induced acute respiratory distress syndrome by inhibiting cytokine storm, oxidative stress via modulating the MAPK/NF-κB pathway."
2.	Liver Cirrhosis (Hepatic Cirrhosis) 12/15/2022 - "Dehydrozingerone ameliorates thioacetamide-induced liver fibrosis via inhibition of hepatic stellate cells activation through modulation of the MAPK pathway."
3.	Cytokine Release Syndrome 11/01/2021 - "Dehydrozingerone ameliorates Lipopolysaccharide induced acute respiratory distress syndrome by inhibiting cytokine storm, oxidative stress via modulating the MAPK/NF-κB pathway."
4.	Cognitive Dysfunction 10/01/2020 - "Dehydrozingerone protects temozolomide-induced cognitive impairment in normal and C6 glioma rats besides enhancing its anticancer potential." 10/01/2020 - "Considering the cognitive impairment induced by temozolomide (TMZ) in glioblastoma survivors, the present study was aimed to evaluate the protective effect of dehydrozingerone (DHZ) against TMZ-induced cognitive impairment (chemobrain) and C6 cell line-induced glioma in male Wistar rats. " 11/15/2021 - "For the first time, this review focuses on the published effects of astaxanthin, omega-3 fatty acids, ginsenoside, cotinine, resveratrol, polydatin, catechin, rutin, naringin, curcumin, dehydrozingerone, berberine, C-phycocyanin, the higher fungi Cordyceps militaris, thyme (Thymus vulgaris) and polyherbal formulation Mulmina™ in mitigating cognitive impairments in preclinical models of study, and also addresses their potential neuro-therapeutic mechanisms and applications in preventing/ameliorating chemobrain."
5.	Glioma (Gliomas) 10/01/2020 - "Dehydrozingerone protects temozolomide-induced cognitive impairment in normal and C6 glioma rats besides enhancing its anticancer potential." 10/01/2020 - "Considering the cognitive impairment induced by temozolomide (TMZ) in glioblastoma survivors, the present study was aimed to evaluate the protective effect of dehydrozingerone (DHZ) against TMZ-induced cognitive impairment (chemobrain) and C6 cell line-induced glioma in male Wistar rats. " 12/01/2023 - "The aim of our study was to investigate the potential of rutin, catechin, dehydrozingerone, naringenin, and quercetin, both alone and in combination with temozolomide, to inhibit the expression of O6-methylguanine-DNA methyltransferase (MGMT) in glioma cells. "

Related Drugs and Biologics

1.	Thioacetamide (Thioacetamid)
2.	Lipopolysaccharides
3.	Curcumin
4.	Rutin (Rutoside)
5.	Catechin (Z 7300)
6.	Temozolomide (Temodar)
7.	Ginsenosides
8.	Omega-3 Fatty Acids (Omega 3 Fatty Acids)
9.	Quercetin
10.	Phycocyanin

Related Therapies and Procedures

1.	Therapeutics