HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

trimethylarsine oxide

sodium arsenate metabolite in fish

Networked: 5 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Fukushima, Shoji: 2 articles (08/2004 - 07/2002)
2.	Kinoshita, Anna: 2 articles (08/2004 - 07/2002)
3.	Morimura, Keiichirou: 2 articles (08/2004 - 07/2002)
4.	Wanibuchi, Hideki: 2 articles (08/2004 - 07/2002)
5.	Shiue, Ivy: 1 article (12/2015)
6.	Liu, Jie: 1 article (09/2008)
7.	Waalkes, Michael P: 1 article (09/2008)
8.	Dopp, E: 1 article (09/2005)
9.	Florea, A M: 1 article (09/2005)
10.	Hartmann, L M: 1 article (09/2005)

Related Diseases

1.	Carcinogenesis 07/10/2002 - "The present study was conducted to determine the promoting effects of organic arsenicals related to DMA [monomethylarsonic acid (MMA) and trimethylarsine oxide (TMAO)] on rat liver carcinogenesis using a liver medium-term bioassay (the Ito test). " 08/01/2004 - "In our attempts to clarify DMA carcinogenicity, we have recently shown carcinogenic effects of DMA and its related metabolites using various experimental protocols in rats and mice: (1) a multi-organ promotion bioassay in rats; (2) a two-stage promotion bioassay by DMA of rat urinary bladder and liver carcinogenesis; (3) a 2-year carcinogenicity test of DMA in rats; (4) studies on the effects of DMA on lung carcinogenesis in rats; (5) promotion of skin carcinogenesis by DMA in keratin (K6)/ornithine decarboxylase (ODC) transgenic mice; (6) carcinogenicity of DMA in p53(+/-) knockout and Mmh/8-OXOG-DNA glycolase (OGG1) mutant mice; (7) promoting effects of DMA and related organic arsenicals in rat liver; (8) promoting effects of DMA and related organic arsenicals in a rat multi-organ carcinogenesis test; and (9) 2-year carcinogenicity tests of monomethylarsonic acid (MMA) and trimethylarsine oxide (TMAO) in rats. "
2.	Hepatocellular Carcinoma (Hepatoma) 09/01/2005 - "In the present study, we investigated cyto-/genotoxic effects of the arsenic compounds arsenate [As(i)(V)], arsenite [As(i)(III)], monomethylarsonic acid [MMA(V)], monomethylarsonous acid [MMA(III)], dimethylarsinic acid [DMA(V)], dimethylarsinous acid [DMA(III)], and trimethylarsine oxide [TMAO(V)] after an extended exposure time (24 h) and compared the uptake capabilities of fibroblasts (CHO-9 cells: Chinese hamster ovary) used for genotoxicity studies, with those of hepatic cells (Hep G2: hepatoma cell-line). "
3.	Neoplasms (Cancer) 09/01/2008 - "In rats, the methylated arsenicals, dimethylarsinic acid promotes diethylnitrosamine-initiated liver tumors, whereas trimethylarsine oxide induces liver adenomas. "
4.	Eczema 12/01/2015 - "Adults with ever eczema were found to have higher levels of urinary trimethylarsine oxide concentrations (PAR 7.0%) but not other speciated arsenic concentrations. " 12/01/2015 - "IgE antibodies and urinary trimethylarsine oxide accounted for 1-7% population attributable risks for eczema in adults: USA NHANES 2005-2006."
5.	Adenoma (Adenomas) 09/01/2008 - "In rats, the methylated arsenicals, dimethylarsinic acid promotes diethylnitrosamine-initiated liver tumors, whereas trimethylarsine oxide induces liver adenomas. "

Related Drugs and Biologics

1.	Arsenicals (Arsenic Compounds)
2.	monomethylarsonic acid (MSMA)
3.	trimethyloxamine (trimethylamine N-oxide)
4.	Cacodylic Acid (Cacodylate)
5.	Ornithine Decarboxylase (Decarboxylase, Ornithine)
6.	Keratins (Keratin)
7.	DNA (Deoxyribonucleic Acid)
8.	dimethylarsinous acid
9.	monomethylarsonous acid
10.	arsenic acid (arsenate)