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doxorubicin-heparin

one mole of heparin binds 16 moles of doxorubicin; potential antineoplastic agent

Also Known As:

adriamycin-heparin; heparin-doxorubicin

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Geng, Yanyan: 1 article (03/2013)
2.	Gu, Zhongwei: 1 article (03/2013)
3.	Guo, Chunhua: 1 article (03/2013)
4.	Li, Ning: 1 article (03/2013)
5.	Luo, Kui: 1 article (03/2013)
6.	She, Wenchuan: 1 article (03/2013)
7.	Wang, Gang: 1 article (03/2013)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2013 - "Dendronized heparin-doxorubicin conjugate based nanoparticle as pH-responsive drug delivery system for cancer therapy." 01/01/1988 - "[Action of doxorubicin and a doxorubicin-heparin complex on the growth and metastasis of experimental tumors and the hemostatic system indices]." 08/15/2023 - "However, by utilizing doxorubicin molecules to produce reactive oxygen species (ROS), we found that the heparin-doxorubicin conjugates have significant cytotoxic ability to kill CT26 tumor cells with low anticoagulant activity. "
2.	Cardiotoxicity 01/01/1995 - "We have compared the antitumor activity and cardiotoxicity of free doxorubicin (Dox) and doxorubicin-heparin complex in vivo and in vitro. " 01/01/1995 - "Doxorubicin-heparin complex: reduction of cardiotoxicity of doxorubicin."
3.	Sarcoma (Soft Tissue Sarcoma) 01/01/1988 - "In experiments on rats with the Pliss lymphosarcoma and sarcoma 45 the doxorubicin-heparin complex depressed more efficiently the tumour growth and metastasis spreading. "
4.	Neoplasm Metastasis (Metastasis) 01/01/1988 - "In experiments on rats with the Pliss lymphosarcoma and sarcoma 45 the doxorubicin-heparin complex depressed more efficiently the tumour growth and metastasis spreading. " 01/01/1988 - "[Action of doxorubicin and a doxorubicin-heparin complex on the growth and metastasis of experimental tumors and the hemostatic system indices]."
5.	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/01/1988 - "In experiments on rats with the Pliss lymphosarcoma and sarcoma 45 the doxorubicin-heparin complex depressed more efficiently the tumour growth and metastasis spreading. "

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)
2.	Reactive Oxygen Species (Oxygen Radicals)
3.	Hemostatics (Antihemorrhagics)
4.	Electrolytes
5.	Anticoagulants

Related Therapies and Procedures

1.	Therapeutics