gambogic acid

12/01/2014 - "Gambogic acid is a potent anticancer agent and has been found effective against various types of cancer cells. "
04/01/2014 - "Gambogic acid (GA) has been approved for Phase II clinical trials in cancer therapy in China. "
09/01/2013 - "The anti-cancer activity of gambogic acid has been tested in in vitro and in vivo studies. "
02/01/2013 - "In this study, Lf nanoparticles were firstly used as carriers of gambogic acid (GA) to enhance oral absorption and anti-cancer activity, hence reducing the related toxic effect. "
01/31/2013 - "Gambogic acid (GA) is a natural compound derived from Chinese herbs that has been approved by the Chinese Food and Drug Administration for clinical trials in cancer patients; however, its molecular targets have not been thoroughly studied. "

01/01/2012 - "The aim of the current study was to evaluate the efficacy of a drug delivery system utilizing gambogic acid-loaded magnetic Fe(3)O(4) nanoparticles (GA-MNP-Fe(3)O(4)) on the suppression of ETS1-mediated cell proliferation and migration in Panc-1 pancreatic cancer cells. "
01/01/2011 - "Study of the enhanced anticancer efficacy of gambogic acid on Capan-1 pancreatic cancer cells when mediated via magnetic Fe3O4 nanoparticles."
01/01/2012 - "Gambogic acid-loaded magnetic Fe(3)O(4) nanoparticles inhibit Panc-1 pancreatic cancer cell proliferation and migration by inactivating transcription factor ETS1."
11/01/2014 - "Single-walled carbon nanotube and graphene nanodelivery of gambogic acid increases its cytotoxicity in breast and pancreatic cancer cells."
11/01/2014 - "Graphene and single-walled carbon nanotubes were used to deliver the natural low-toxicity drug gambogic acid (GA) to breast and pancreatic cancer cells in vitro, and the effectiveness of this complex in suppressing cellular integrity was assessed. "

06/01/2012 - "Enhancement of anticancer efficacy of chemotherapeutics by gambogic acid against gastric cancer cells."
06/28/2005 - "Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823."
06/28/2005 - "To investigate the anticancer effect of a traditional Chinese medicine gambogic acid (GA) in human gastric cancer line BGC-823 and further study the mechanism of apoptosis induction of GA. "
04/18/2008 - "In this study, we examined the ability of gambogic acid (GA) to reverse docetaxel resistance in BGC-823/Doc gastric cancer cells. "
04/18/2008 - "Gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells."

01/01/2012 - "This study aimed to assess the interaction between gambogic acid and docetaxel on human gastrointestinal cancer cells and to investigate the mechanism of gambogic acid plus docetaxel treatment-induced apoptotic cell death. "
01/01/2012 - "The combined application of gambogic acid and docetaxel enhanced apoptosis in gastrointestinal cancer cells. "
01/01/2012 - "Synergistic anti-proliferative effects of gambogic acid with docetaxel in gastrointestinal cancer cell lines."
01/01/2012 - "Gambogic acid plus docetaxel produced a synergistic anti-tumor effect in gastrointestinal cancer cells, suggesting that the drug combination may offer a novel treatment option for patients with gastric and colorectal cancers."

11/01/2015 - "Gambogic acid inhibits growth, induces apoptosis, and overcomes drug resistance in human colorectal cancer cells."
05/28/2015 - "Gambogic acid induces apoptosis and inhibits colorectal tumor growth via mitochondrial pathways."
01/01/2014 - "ROS-mediated autophagy induced by dysregulation of lipid metabolism plays a protective role in colorectal cancer cells treated with gambogic acid."
01/01/2012 - "Gambogic acid has a marked anti-tumor effect for gastric and colorectal cancers in vitro and in vivo. "
01/01/2012 - "Gambogic acid plus docetaxel produced a synergistic anti-tumor effect in gastrointestinal cancer cells, suggesting that the drug combination may offer a novel treatment option for patients with gastric and colorectal cancers."