pholasin

protein-bound luciferin from mollusk Pholas dactylus which reacts with luciferase & molecular oxygen to produce light; also a bioluminescent indicator for detecting activation of single neutrophils

Also Known As:

Pholasin

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - Firefly Luciferin: 2
      - pholasin: 3
- Luciferins: 114
  - Firefly Luciferin: 2
    - pholasin: 3
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - Firefly Luciferin: 2
        pholasin: 3

Experts

1.	Ferro, Albert: 1 article (09/2011)
2.	Gkaliagkousi, Eugenia: 1 article (09/2011)
3.	Passacquale, Gabriella: 1 article (09/2011)
4.	Ritter, James: 1 article (09/2011)
5.	Shah, Ashish: 1 article (09/2011)
6.	Abel, Martin: 1 article (11/2005)
7.	Elsner, Peter: 1 article (11/2005)
8.	Hipler, Uta-Christina: 1 article (11/2005)
9.	Klemm, Dieter: 1 article (11/2005)
10.	Schönfelder, Ute: 1 article (11/2005)

Related Diseases

1.	Wounds and Injuries (Trauma) 11/01/2005 - "Antioxidant capacity of the investigated wound dressing was determined by a pholasin-based chemiluminescent assay. "
2.	Heart Failure 09/01/2011 - "In platelets from patients with heart failure due to idiopathic dilated cardiomyopathy (n= 16) and healthy control subjects (n= 23), NO synthase (NOS) activity was evaluated by L-[(3)H]-arginine to l-[(3)H]-citrulline conversion, cGMP was determined by radioimmunoassay, vasodilator-stimulated phosphoprotein (VASP: total and serine-239-phosphorylated) was assessed by western blotting, and O(2)(-) production and O(2)(-) scavenging capacity were measured by pholasin-enhanced chemiluminescence. "
3.	Chronic Granulomatous Disease 01/01/1992 - "No taurine-chloramine was detected in supernatants of lymphocytes and PMN from patients with an oxidative burst defect (chronic granulomatous disease, CGD) with the KI method, but Pholasin-dependent CL was consistently observed. "
4.	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 09/01/2011 - "In platelets from patients with heart failure due to idiopathic dilated cardiomyopathy (n= 16) and healthy control subjects (n= 23), NO synthase (NOS) activity was evaluated by L-[(3)H]-arginine to l-[(3)H]-citrulline conversion, cGMP was determined by radioimmunoassay, vasodilator-stimulated phosphoprotein (VASP: total and serine-239-phosphorylated) was assessed by western blotting, and O(2)(-) production and O(2)(-) scavenging capacity were measured by pholasin-enhanced chemiluminescence. "

Related Drugs and Biologics

1.	Nitric Oxide Synthase (NO Synthase)
2.	Serine (L-Serine)
3.	Citrulline
4.	Arginine (L-Arginine)
5.	Antioxidants
6.	vasodilator-stimulated phosphoprotein
7.	N-chlorotaurine