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cefprozil (Cefzil)

structure given in first source

Also Known As:

Cefzil; 7-(2-amino-2-(4-hydroxyphenyl)acetamido)-3-(propenyl)-3-cephem-4-carboxylic acid monohydrate; Arzimol; BMY 28100; BMY-28100; Belmac brand of cefprozil; Brisoral; Bristol-Myers Squibb brand of cefprozil; Bristol-Myers brand of cefprozil; Mead Johnson brand of cefprozil monohydrate; Procef; cefprozil monohydrate

Networked: 101 relevant articles (11 outcomes, 25 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Pichichero, Michael E: 3 articles (03/2007 - 04/2005)
2.	Brook, Itzhak: 3 articles (04/2005 - 07/2004)
3.	Blumer, Jeffrey L: 2 articles (01/2007 - 01/2005)
4.	Dul, Michael: 2 articles (01/2007 - 01/2005)
5.	Toltzis, Hasida: 2 articles (01/2007 - 01/2005)
6.	O'Riordan, Mary Ann: 2 articles (01/2007 - 01/2005)
7.	Toltzis, Philip: 2 articles (01/2007 - 01/2005)
8.	Mukherjee, Abhijit: 2 articles (07/2004 - 04/2004)
9.	Gupta, Nomeeta: 2 articles (07/2004 - 04/2004)
10.	Tack, K J: 2 articles (12/2000 - 06/2000)

Related Diseases

1.	Infection 08/01/1987 - "BMY-28100 was also more potent against infections of H. " 10/01/1996 - "Safety and efficacy of cefprozil as part of a parenteral-oral antibiotic regimen for the treatment of suppurative skeletal infections in children." 12/01/1992 - "[Clinical studies on cefprozil granules in pediatric skin soft tissues infections]." 06/01/1992 - "Clinical trials of cefprozil for treatment of skin and skin-structure infections: review." 07/01/2004 - "Streptococcal tonsillopharyngitis, which is a common infection has been well treated with cefprozil, a novel third generation cephalosporin. "
2.	Otitis Media 05/01/1997 - "We identified the pathogens causing persistent and recurrent acute otitis media (AOM) and the clinical efficacy of cefprozil as treatment. " 04/01/2004 - "Present study is an effort to study the efficacy and safety of cefprozil in children with acute otitis media. " 01/01/2007 - "Despite the wide-scale use of cefprozil for acute otitis media (AOM), there are only limited data available regarding the pharmacokinetic profile of this agent in the pediatric population. " 01/01/2007 - "Pharmacokinetics of cefprozil in plasma and middle ear fluid: in children undergoing treatment for acute otitis media." 04/01/2004 - "In conclusion, cefprozil is a well tolerated and effective drug for acute otitis media in children. "
3.	Pharyngitis (Sore Throat) 08/01/1993 - "Cefprozil can be considered a safe and reliable drug for the treatment of streptococcal pharyngitis in children." 10/01/1994 - "Four multicenter randomized clinical trials were conducted to compare the clinical efficacy and safety of cefprozil administered once or twice a day for the treatment of mild to moderate GABHS tonsillitis and pharyngitis. " 05/01/1993 - "The cefprozil concentrations in either the tonsillar or the adenoidal tissue at both dose levels over 3.17 h after dosing are much higher than the MICs for common pathogens which cause pharyngitis or tonsillitis." 06/01/1992 - "Treatment of pharyngitis and tonsillitis with cefprozil: review of three multicenter trials." 01/01/1998 - "Our objective was to perform a prospective, randomized, double blinded study of cefprozil and penicillin therapy to eradicate group A beta-hemolytic streptococci (GABHS) in children who were bacteriologic failures after receiving a standard 10-day course of penicillin treatment for GABHS pharyngitis. "
4.	Tonsillitis 10/01/1994 - "Four multicenter randomized clinical trials were conducted to compare the clinical efficacy and safety of cefprozil administered once or twice a day for the treatment of mild to moderate GABHS tonsillitis and pharyngitis. " 05/01/1993 - "The cefprozil concentrations in either the tonsillar or the adenoidal tissue at both dose levels over 3.17 h after dosing are much higher than the MICs for common pathogens which cause pharyngitis or tonsillitis." 06/01/1992 - "Treatment of pharyngitis and tonsillitis with cefprozil: review of three multicenter trials." 11/01/2001 - "The bacteriologic eradication rate was significantly greater with cefprozil compared with erythromycin in children with pharyngitis/tonsillitis. " 02/01/1993 - "The clinical efficacy of cefprozil is similar to that of cefaclor in patients with tonsillitis or pharyngitis but the bacteriological efficacy of cefprozil is significantly greater than that of cefaclor. "
5.	Urinary Tract Infections (Urinary Tract Infection) 03/01/1992 - "Cefprozil is a new oral cephalosporin with an in vitro spectrum of activity that includes the pathogens most commonly associated with acute and uncomplicated urinary tract infections (UTIs). " 10/01/1991 - "Cefprozil, 500 mg once daily, appears to be an appropriate alternative for the treatment of acute, uncomplicated urinary tract infections." 11/01/1995 - "The results of this in vitro study indicate that oral administration of cefprozil might be efficacious in the treatment of community-acquired cutaneous, respiratory and urinary tract infections." 02/01/2004 - "After acute urinary tract infections (UTIs) were treated, the patients were divided into 3 groups randomly and TMP/SMZ was given to 21 patients, cephadroxil was given to 25 patients and cefprozil was given to 34 patients for 3 months--one dose at night. " 02/01/2004 - "Comparison of trimethoprim-sulfamethoxazole, cephadroxil and cefprozil as prophylaxis for recurrent urinary tract infections in children."

Related Drugs and Biologics

1.	Cefaclor (Ceclor)
2.	cefdinir (CFDN)
3.	Amoxicillin (Wymox)
4.	Clavulanic Acid (Potassium Clavulanate)
5.	Erythromycin (Erycette)
6.	Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)
7.	Thymidine Monophosphate (TMP)
8.	Cephalosporins (Cephalosporin Antibiotics)
9.	Cefuroxime (Zinacef)
10.	cefpodoxime

Related Therapies and Procedures

1.	Oral Administration
2.	Adenoidectomy
3.	Antibiotic Prophylaxis
4.	Aftercare (After-Treatment)