E 0747

06/01/1987 - "The class 1 property of E-0747 was also shown in a newly developed locally-induced digitalis arrhythmia. "
06/01/1987 - "The minimum effective plasma concentration of E-0747 was determined for the first three arrhythmia models. "
06/01/1987 - "Antiarrhythmic effects of a new drug, E-0747, on canine ventricular arrhythmia models."
06/01/1987 - "Thus E-0747 suppresses arrhythmia by inhibiting Na channels of cardiac cells and is expected to become a clinically useful antiarrhythmic drug."
06/01/1987 - "Antiarrhythmic effects of a new antiarrhythmic drug, E-0747, were examined using four canine ventricular arrhythmia models: digitalis-, adrenaline- and two-stage coronary ligation-induced arrhythmias and a newly developed locally-induced digitalis arrhythmia. "