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somatotropin-binding protein (growth hormone-binding protein)

found in serum of vertebrates; not a receptor; RefSeq NM_010284 (mouse)
Also Known As:
growth hormone-binding protein; GH-binding protein; GHR protein, human; Ghr protein, mouse; circulating growth hormone-binding protein; growth hormone-binding protein, human; growth hormone-binding protein, mouse; hGH BP; serum binding protein, human; somatropin-binding protein
Networked: 134 relevant articles (1 outcomes, 14 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Strasburger, C J: 2 articles (12/2005 - 12/2001)
2. Andersen, Ove: 2 articles (12/2004 - 01/2004)
3. Andersen, Ulrik B: 2 articles (12/2004 - 01/2004)
4. Flyvbjerg, Allan: 2 articles (12/2004 - 01/2004)
5. Hansen, Birgitte R: 2 articles (12/2004 - 01/2004)
6. Haugaard, Steen B: 2 articles (12/2004 - 01/2004)
7. Iversen, Johan: 2 articles (12/2004 - 01/2004)
8. Madsbad, Sten: 2 articles (12/2004 - 01/2004)
9. Orskov, Hans: 2 articles (12/2004 - 01/2004)
10. Raynaud-Simon, A: 2 articles (01/2003 - 05/2002)

Related Diseases

1. Body Weight (Weight, Body)
05/01/2001 - "Blood growth hormone-binding protein levels in premenopausal and postmenopausal women: roles of body weight and estrogen levels."
03/01/1993 - "Analysis of variance revealed a significant negative effect of Type 1 diabetes on serum levels of the growth hormone-binding protein and of insulin-like growth factor I. In the diabetic patients, serum levels of the growth hormone-binding protein were positively related to body mass index and to insulin dose per kg body weight, and were not influenced by pubertal stage, gender, or plasma levels of haemoglobin A1c. "
02/01/2003 - "Body weight (P < 0.003), lean body mass (P < 0.006), D-xylose absorption (P < 0.02), insulin-like growth factor 1 (P < 0.002), and insulin-like growth factor binding protein 3 (P < 0.002) increased, whereas uptake of GH binding protein decreased (P < 0.01), without any major adverse effect. "
09/01/2003 - "Relative to the control group, women of the intervention group showed a significant reduction of body weight, waist circumference, fasting serum levels of testosterone, C peptide, glucose, and insulin area after glucose tolerance test, and a significant increase of serum levels of sex hormone-binding globulin, IGFBP-1, -2, and growth hormone-binding protein. "
01/01/2023 - "Liver was assessed for histopathology, apoptosis (terminal deoxynucleotidyl transferase dUTP nick end labeling, TUNEL stain), and GH, insulin-like growth factor (IGF)-I, GH binding protein (GHBP), and IGF binding protein (IGFBP)-3. Neonatal IH resulted in decreased liver weight and liver/body weight ratios, as well as hepatocyte swelling, steatosis, and apoptosis, which were attenuated with fish oil, nGSH, and combined fish oil+CoQ10. "
2. Acromegaly
3. Laron Syndrome (Syndrome, Laron)
4. Type 1 Diabetes Mellitus (Autoimmune Diabetes)
5. Dwarfism

Related Drugs and Biologics

1. Insulin (Novolin)
2. Glucose (Dextrose)
3. C-Peptide
4. Insulin-Like Growth Factor Binding Protein 1
5. Testosterone (Sustanon)
6. Sex Hormone-Binding Globulin
7. Insulin-Like Growth Factor I (IGF-1)
8. Insulin-Like Growth Factor Binding Proteins
9. Growth Hormone (Somatotropin)
10. Insulin-Like Peptides

Related Therapies and Procedures

1. Therapeutics
2. Gluten-Free Diet
3. Caloric Restriction