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CGP 20376
Also Known As:
CGP-20376; N-(2-tert-butyl-5-methoxybenzothiazol-6-yl)dithiocarbonic acid 5-(1-carboxyethyl)ether
Networked:
3
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiazoles: 392
CGP 20376: 3
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Thiazoles: 392
CGP 20376: 3
Related Diseases
1.
Filariasis
06/01/1991 - "
This study was designed to investigate the activity of CGP 20376, a benzothiazole derivative, against Brugia malayi in jirds and to illustrate the utility of parasite antigen detection as a means of monitoring drug efficacy in filariasis.
"
2.
Infections
03/01/1987 - "
Multimammate rats (Mastomys natalensis) infected with Litomosoides carinii were treated 65 days after infection with a single oral dose of 50 mg/kg of CGP 20308 or CGP 20376 (Ciba Geigy Limited, Basel).
"
12/01/1988 - "
There were several similarities (Mel W, CGP 20376, CGP 6140, levamisole) and two differences (suramin, furapyrimidone) between levels of drug efficacy in this model and activity against natural infections of O.
"
Related Drugs and Biologics
1.
Antigens
2.
benzothiazole
3.
Suramin (Suramin Sodium)
4.
Levamisole (Decaris)
5.
CGP 20308
6.
amocarzine
7.
furapyrimidone
8.
melarsonic acid (melarsonyl potassium)