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acromelic acid A

isolated from poisonous mushroom Clitocybe acromelaga; structure given in first source

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - Kainic Acid: 3549
      - acromelic acid A: 7

Experts

1.	Ito, Seiji: 5 articles (08/2015 - 06/2004)
2.	Minami, Toshiaki: 5 articles (08/2015 - 06/2004)
3.	Matsumura, Shinji: 3 articles (08/2015 - 06/2004)
4.	Furuta, Kyoji: 3 articles (06/2013 - 12/2007)
5.	Suzuki, Masaaki: 3 articles (06/2013 - 12/2007)
6.	Miyazaki, Shinichiro: 2 articles (08/2015 - 06/2013)
7.	Doi, Hisashi: 2 articles (06/2013 - 04/2011)
8.	Kanazawa, Masakatsu: 2 articles (06/2013 - 04/2011)
9.	Kitano, Manabu: 1 article (08/2015)
10.	Omoto, Haruka: 1 article (08/2015)

Related Diseases

1.	Hyperalgesia 08/05/2015 - "We previously showed that intrathecal administration of acromelic acid A (ACRO-A) provoked tactile allodynia in mice. " 08/05/2015 - "Comparison of mechanisms of allodynia induced by acromelic acid A between early and late phases." 04/01/2011 - "The tracer is potentially useful as a tool to investigate the mode of action of acromelic acid A in the induction of allodynia." 04/01/2011 - "Synthesis of an acromelic acid A analog-based 11C-labeled PET tracer for exploration of the site of action of acromelic acid A in allodynia induction." 06/15/2013 - "We previously demonstrated that intrathecal (i.t.) administration of acromelic acid A (Acro-A) induced allodynia in mice and that simultaneous administration of (2S,3R,4R)-3-carboxymethyl-4-(phenylthio)pyrrolidine-2-carboxylic acid (PSPA-1), an Acro-A analogue, attenuated the Acro-A-induced allodynia. "
2.	Spastic Paraparesis 12/01/1991 - "A single systemic injection of acromelic acid, a novel kainate analogue, caused long-lasting spastic paraparesis in the rat. "
3.	Paraparesis 05/01/1992 - "Acromelic acid, a novel kainate analogue, induces long-lasting paraparesis with selective degeneration of interneurons in the rat spinal cord."
4.	Pain (Aches) 12/01/2007 - "administration of acromelic acid-A (ACRO-A), a Japanese mushroom poison, provoked prominent tactile pain (allodynia) at an extremely low dose of 1 fg/mouse. "

Related Drugs and Biologics

1.	Kainic Acid (Kainate)
2.	Poisons
3.	(2S,3R,4R)- 3- carboxymethyl- 4- (phenylthio)pyrrolidine- 2- carboxylic acid
4.	pyrrolidine