arginyl-glycyl-aspartic acid directed cell adhesion receptor
class of divalent cation-dependent receptors that recognizes sequence Arg-Gly-Asp in adhesive protein; examples are fibronectin & vitronectin receptors
Also Known As:
Arg-Gly-Asp directed cell adhesion receptors; RGD receptor; adhesive glycoprotein receptor; receptor, Arg-Gly-Asp DCA
Networked: 4
relevant articles (0 outcomes,
2 trials/studies)
Bio-Agent Context: Research Results
Experts
| 1. | Hoberück, Sebastian:
1 article
(10/2020)
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| 2. | Kotzerke, Jörg:
1 article
(10/2020)
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| 3. | Notni, Johannes:
1 article
(10/2020)
|
| 4. | Quigley, Neil Gerard:
1 article
(10/2020)
|
| 5. | Richter, Frauke:
1 article
(10/2020)
|
| 6. | Steiger, Katja:
1 article
(10/2020)
|
| 7. | Weichert, Wilko:
1 article
(10/2020)
|
| 8. | Meng, Jie:
1 article
(06/2020)
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| 9. | Wang, Han:
1 article
(06/2020)
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| 10. | Xu, Yan Hong:
1 article
(06/2020)
|
Related Diseases
| 1. | Neoplasms (Cancer)
06/30/2020
- " The specificity of Fe3O4-PEG-RGD to bind RGD receptor was investigated in vitro by HepG2 cellular uptake and cell MR imaging, and in vivo by MR imaging of subcutaneous HepG2 tumors of nude mice.Results" 10/31/2020
- " As a major activator of transforming growth factor β (TGF-β), the RGD receptor αvβ8-integrin is involved in pathogenic processes related to TGF-β dysregulation, such as tumor growth, invasion, and radiochemoresistance, metastasis and tumor cell stemness, as well as epithelial-mesenchymal transition. " 12/01/2018
- " Furthermore, in vitro and in vivo studies reveal that both these prodrug nanocarriers could selectively deliver doxorubicin to RGD receptor-overexpressing cancer cells, leading to longer blood retention time, enhanced antitumor efficacy, and reduced systematic toxicity in murine tumor model, suggesting their potential application for targeted drug delivery."
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| 2. | Lung Neoplasms (Lung Cancer)
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| 3. | Neoplasm Metastasis (Metastasis)
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Related Drugs and Biologics
Related Therapies and Procedures