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naphthalenesulfonamide

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - naphthalenesulfonamide: 6
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - naphthalenesulfonamide: 6

Experts

1.	Bian, Jianchun: 1 article (10/2019)
2.	Chile, Chung: 1 article (10/2019)
3.	Gu, Jianhong: 1 article (10/2019)
4.	Liu, Zongping: 1 article (10/2019)
5.	Ma, Yonggang: 1 article (10/2019)
6.	Song, Ruilong: 1 article (10/2019)
7.	Wang, Chao: 1 article (10/2019)
8.	YanYuan,: 1 article (10/2019)
9.	Zhao, Hongyan: 1 article (10/2019)
10.	Zheng, Jiaming: 1 article (10/2019)

Related Diseases

1.	Carcinoma (Carcinomatosis) 12/15/1987 - "The present study was designed to potentiate the antineoplastic effects of cisplatin by combination with calmodulin antagonists [N-(6-amino-hexyl)-5-chloro-1-naphthalenesulfonamide (W-7) and N-(6-aminohexyl)-1-naphthalenesulfonamide (W-5)] in nude mice bearing human ovarian carcinoma. "
2.	Neoplasms (Cancer) 01/01/2016 - "N-(2-methyl-indol-1H-5-yl)-1-naphthalenesulfonamide: A novel reversible antimitotic agent inhibiting cancer cell motility." 02/01/1984 - "Potent antitumor promoting activity of N-6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, in mouse skin tumor formation induced by 7,12-dimethylbenz[a]anthracene plus teleocidin."
3.	Hemophilia A (Haemophilia) 11/01/2011 - "Potential agents were generated by synthesizing specific inhibitors [6-(Lys-Lys-Thr-[homo]Arg)amino-2-(Lys[carbobenzoxy]-Lys[carbobenzoxy]-O-benzyl)naphthalenesulfonamide] (PNASN-1)] for activated protein C (APC) and tested in plasma and fresh blood from hemophilia A patients. "
4.	Hemolysis 05/01/1991 - "PIC, TFP and two other CMA, W7 and N-(4-aminobutyl)-5-chloro-1-naphthalenesulfonamide) failed consistently to inhibit 48/80-induced HR from RPMC, and when used on their own at high concentration these compounds caused HR. PIC and TFP also potentiated the heat-induced haemolysis of rat erythrocytes, i.e. "
5.	Bone Resorption 10/15/2019 - "1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis (acetoxymethyl ester) (BAPTA-AM)/N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride (W-7) partly or absolutely recovered osteoprotegerin-induced osteoclasts adhesion structure damage, including increased the PYK2 and SRC phosphorylation, changed the distribution of PYK2/SRC and integrinαvβ3, and inhibited retraction of lamellipodia and filopodia and recovered osteoclast bone resorption activity. "

Related Drugs and Biologics

1.	Calmodulin (Calcium-Dependent Activator Protein)
2.	Cisplatin (Platino)
3.	Antineoplastic Agents (Antineoplastics)
4.	N- (6- aminohexyl)- 1- naphthalenesulfonamide (W-5)
5.	Osteoprotegerin
6.	Antimitotic Agents
7.	Protein C
8.	Esters
9.	1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester
10.	anthracene