2-tert-butyl-4-quinone

a metabolite of butylated hydroxyanisole ; structure given in first source

Also Known As:

2-t-BQ; 2-tert-butyl(1,4)para-quinone; 2-tert-butyl-1,4-benzoquinone; 2-tert-butyl-4-benzoquinone; tert-butylquinone; 2,5-Cyclohexadiene-1,4-dione, 2-(1,1-dimethylethyl)-

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Quinones: 434
  - Benzoquinones: 25
    - 2-tert-butyl-4-quinone: 4

Experts

1.	Banković, Jasna: 1 article (08/2016)
2.	Dinić, Jelena: 1 article (08/2016)
3.	Jeremić, Marko: 1 article (08/2016)
4.	Novaković, Irena: 1 article (08/2016)
5.	Pešić, Milica: 1 article (08/2016)
6.	Sladić, Dušan: 1 article (08/2016)
7.	Šegan, Dejan: 1 article (08/2016)
8.	El-Kabbani, Ossama: 1 article (01/2012)
9.	Endo, Satoshi: 1 article (01/2012)
10.	Hara, Akira: 1 article (01/2012)

Related Diseases

1.	Chromosome Aberrations (Chromosome Abnormalities) 01/01/2012 - "BHQ is metabolized into cytotoxic tert-butylquinone (BQ), which is further converted to 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one (TBEH) through 6-tert-butyl-2,3-epoxy-4-benzoquinone (TBE), which induces chromosomal aberration. " 06/01/1990 - "In addition to the above 4 chemicals, 3-tert-butyl-4,5-dihydroxyanisole (BHA-OH), 3-tert-butylanisole-4,5-quinone (BHA-o-Q), and tert-butylquinone oxide (BQO) were tested in the chromosomal aberration test. "
2.	Neoplasms (Cancer) 08/08/2016 - "Two tert-butylquinone derivatives were particularly selective towards MDR cancer cells. "
3.	Leukemia 05/01/2003 - "Cell death induced by the phenolic antioxidant tert-butylhydroquinone and its metabolite tert-butylquinone in human monocytic leukemia U937 cells." 05/01/2003 - "2-tert-Butyl-4-hydroquinone (TBHQ), a phenolic antioxidant used as a food additive, and its metabolite 2-tert-butyl-1,4-benzoquinone (TBQ) were both cytotoxic in human monocytic leukemia U937 cells, TBQ being the more strongly cytotoxic. "

Related Drugs and Biologics

1.	Oxides
2.	Food Additives (Food Additive)
3.	Butylated Hydroxyanisole (BHA)
4.	Antioxidants
5.	3-tert-butyl-4,5-dihydroxyanisole
6.	hydroxide ion
7.	2-tert-butylhydroquinone (tert-butylhydroquinone)