pertussis toxoid

03/01/1998 - "In a previously reported double blind placebo-controlled trial it was shown that vaccination with pertussis toxoid during infancy reduced the incidence of pertussis in the vaccinees. "
01/01/2022 - "pertussis and anti-pertussis toxoid antibody secreting cells increased one day after boost and remained high at day 532. "
06/01/2008 - "Pertussis seroconversion, defined as a > fourfold increase in antibody titre, occurred in 95.3% for anti-pertussis toxoid antibody and in 89.0% for anti-filamentous haemagglutinin antibody. "
04/12/2007 - "In Goteborg Sweden, virtual elimination of pertussis occurred following immunization of 70% of the children less than 10 years old with monocomponent pertussis toxoid (PTx). "
10/01/2001 - "With the aim of studying the epidemiology and transmission of pertussis, mass vaccination with pertussis toxoid of children born during the 1990s was instituted in the Göteborg area (population, 778,597) in 1995. "

10/01/1990 - "These analyses confirm that vaccination with pertussis toxoid alone does protect against typical whooping cough with laboratory confirmation, but show that it does not protect against infection or colonization. "
11/17/1998 - "Our observations suggest that in the immune defense of a natural Bordetella pertussis infection, the Th-1 specific T cell response to filamentous hemagglutinin and particularly to pertussis toxoid may play a major role."
01/01/1991 - "Continued analysis of data from the trial suggests that acellular pertussis vaccines protect against typical illness to the same extent as whole cell vaccines and that protection against infection may be augmented by adding one or more components to a pertussis toxoid-based vaccine. "
06/01/2023 - "pertussis infection and enhanced the efficacy of a current pertussis vaccine containing pertussis toxoid against the cough. "
08/01/2002 - "This study examines the protective effects of priming with tetranitromethane-inactivated pertussis toxoid (PTx) vaccine in the aerosol challenge model and whether a measurable response to a priming dose of PTx is enough to initiate a protective secondary response when challenged with infection. "

11/18/2021 - "Using this tool, we could identify the BCRs related to anti-tetanus and anti-pertussis toxoid BCRs. "
12/01/2001 - "After phase 1 and 2 studies, a randomized, double-blind, placebo-controlled trial of pertussis toxoid (PTox), compounded with diphtheria and tetanus toxoids, was administered to 3450 children according to the Swedish schedule at 3, 5, and 12 months of age. "
01/01/2006 - "There were no differences in diphtheria and tetanus antibodies after vaccination between children who did and did not receive pertussis toxoid. "
01/01/2005 - "Reduced immunogenicity of diphtheria and tetanus toxoids when combined with pertussis toxoid."
10/01/2001 - "Infants were offered 3 doses of pertussis toxoid combined with diphtheria and tetanus toxoids. "

02/11/2011 - "At least 93.6% had anti-diphtheria antibody titers ≥ 0.1 IU/mL. Anti-pertussis toxoid (PT) and anti-filamentous haemagglutinin (FHA) seroconversion (≥ 4-fold increase in antibody titer) rates were 96.6% and 94.4% for Group A, 92.2% and 78.4% for Group B. "
12/01/2021 - "Higher post-booster GMCs were observed in controls versus the Tdap group for anti-filamentous hemagglutinin (1.2-fold), anti-pertussis toxoid (1.5-fold) and anti-diphtheria (1.4-fold). "
12/01/2001 - "After phase 1 and 2 studies, a randomized, double-blind, placebo-controlled trial of pertussis toxoid (PTox), compounded with diphtheria and tetanus toxoids, was administered to 3450 children according to the Swedish schedule at 3, 5, and 12 months of age. "
01/01/2006 - "There were no differences in diphtheria and tetanus antibodies after vaccination between children who did and did not receive pertussis toxoid. "
01/01/2005 - "Reduced immunogenicity of diphtheria and tetanus toxoids when combined with pertussis toxoid."

06/01/2023 - "pertussis infection and enhanced the efficacy of a current pertussis vaccine containing pertussis toxoid against the cough. "