DQ 2556

structure given in first source

Also Known As:

2-(2-aminothiazol-4-yl)-2-(methoxyamino)acetamido-3-(4-(oxazol-5-yl)-1-pyridinio)methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate; DQ-2556; Pyridinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-4-(5-oxazolyl)-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-

Networked: 6 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Related Diseases

1.	Infections 01/01/1993 - "Thus, DQ-2556 appears to be effective for gynecological infections, and the good results were supported by good penetration of the compound into tissues of internal genital organs and retroperitoneal exudate after i.v. or d.i.v." 12/01/1992 - "Against Pseudomonas aeruginosa and Acinetobacter calcoaceticus infections, DQ-2556 was more active than cefuzonam and had activity similar to or less than those of ceftazidime, cefpirome, cefepime, and cefclidin. "
2.	Respiratory Tract Infections (Respiratory Tract Infection) 01/01/1995 - "In vivo, treatment with DQ-2556 was as or more efficacious than that with reference compounds in both systemic and respiratory tract infections in mice. " 08/01/1993 - "These results suggest that DQ-2556 is useful for lower respiratory tract infections, but in patients with kidney failures it is required to seek the most suitable regimen since the excretion rates of the compound decrease as degrees of kidney failure become severer."
3.	Renal Insufficiency (Renal Failure) 08/01/1993 - "These results suggest that DQ-2556 is useful for lower respiratory tract infections, but in patients with kidney failures it is required to seek the most suitable regimen since the excretion rates of the compound decrease as degrees of kidney failure become severer."
4.	Necrosis 05/01/1992 - "A single intravenous administration of a new cephalosporin, DQ-2556, at 1200 mg/kg to Sprague-Dawley rats induced proximal tubular necrosis. " 05/01/1992 - "Furthermore, Ca2+ channel blockers markedly inhibited increases in the serum urea nitrogen and creatinine concentrations and development of the tubular necrosis and the lesions of the arterial walls, which were induced by DQ-2556. "
5.	Escherichia coli Infections 12/01/1992 - "The protective effect of DQ-2556 in experimental gram-positive pathogen and Escherichia coli infections in mice was greater than those of ceftazidime, cefuzonam, cefepime, and cefclidin and was similar to that of cefpirome. "

Related Drugs and Biologics

1.	Urea (Carbamide)
2.	Nitrogen
3.	Creatinine
4.	Cephalosporins (Cephalosporin Antibiotics)
5.	Ceftazidime (Fortum)
6.	Cefpirome (HR 810)
7.	Cefepime (Maxipime)
8.	cefclidin
9.	cefuzonam

Related Therapies and Procedures

1.	Intravenous Administration