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BN 52063
mixture of ginkolide A derivatives; platelet activating factor antagonist isolated from Ginkgo biloba tree
Also Known As:
BN-52063
Networked:
6
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Lactones: 1549
BN 52063: 6
Related Diseases
1.
Exercise-Induced Asthma (Asthma, Exercise Induced)
02/01/1990 - "
The results show that platelet activation after exercise induced asthma was markedly inhibited by BN 52063, indicating that PAF acts as a mediator in exercise induced asthma.
"
01/01/1990 - "
Effects of a PAF-antagonist (BN 52063) on bronchoconstriction and platelet activation during exercise induced asthma.
"
02/01/1990 - "
In a randomised single-blind crossover study we assessed the effects of a specific PAF acether antagonist, BN 52063, on the early asthmatic response to exercise in six patients with exercise induced asthma.
"
01/01/1990 - "
1. The effects of a specific PAF acether antagonist (BN 52063) on the response to isocapnic hyperventilation with dry cold air (ISH study) and exercise (EIA study) were assessed in a single dose and short term treatment study in 10 patients with exercise induced asthma.
"
2.
Hyperventilation
01/01/1990 - "
1. The effects of a specific PAF acether antagonist (BN 52063) on the response to isocapnic hyperventilation with dry cold air (ISH study) and exercise (EIA study) were assessed in a single dose and short term treatment study in 10 patients with exercise induced asthma.
"
3.
Acute Kidney Injury (Acute Renal Failure)
12/01/1991 - "
BN 52063, a platelet-activating factor antagonist, caused a striking change in acute renal failure induced by DDP leading toward normalization of all parameters of renal function.
"
4.
Bronchial Hyperreactivity
11/01/1987 - "
BN 52063 significantly antagonised early bronchoconstriction and showed a tendency to inhibit residual bronchial hyperreactivity, assessed six hours after allergen challenge by a provocation test to acetylcholine.
"
5.
Inflammation (Inflammations)
01/01/1990 - "
4. The gingkolide mixture BN 52063 has recently been reported to inhibit allergen-induced cutaneous inflammation in man; a response which has certain pathological similarities to allergen-induced late-onset airways obstruction in the lung.
"
Related Drugs and Biologics
1.
Platelet Activating Factor
2.
Allergens
3.
Peptide Hydrolases (Proteases)
4.
Acetylcholine (Acetylcholine Chloride)
5.
ginkgolide B