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doxorubicin polyaspartic acid conjugate

bound via methylketone side chain of anthracycline; less hematoxic than doxorubicin

Also Known As:

DX-PAA; doxorubicin poly-L-aspartic acid conjugate

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Neoplasms (Cancer) 01/01/1986 - "Furthermore the observed accumulation of the conjugate and free DX equivalents in the lung and in the liver suggest a possible therapeutic advantages of DX-PAA in tumors with potential metastasis in these organs." 01/01/1986 - "The plasma and tissue distribution of doxorubicin-poly-L-aspartic acid (DX-PAA) and doxorubicin (DX) at equitoxic doses have been studied by a fluorescence assay in tumor bearing mice following administration of a single i.v. bolus injection. "
2.	Neoplasm Metastasis (Metastasis) 01/01/1986 - "Furthermore the observed accumulation of the conjugate and free DX equivalents in the lung and in the liver suggest a possible therapeutic advantages of DX-PAA in tumors with potential metastasis in these organs."

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)
2.	Aspartic Acid (Aspartate)