mediatophore

MW approx. 210 kD; isolated from the presynaptic plasma membranes in the electric organ of Torpedo marmorata

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Neuroblastoma 01/01/2009 - "Reconstituted in liposomes, Xenopus oocytes, and neuroblastoma cells, mediatophore releases acetylcholine in a Ca(2+)-dependent and quantal manner, mimicking physiological release. " 03/01/1996 - "Evoked acetylcholine release expressed in neuroblastoma cells by transfection of mediatophore cDNA."
2.	Fatigue 09/01/1987 - "Activation and desensitization of release could be attributed to the recently identified presynaptic membrane protein, the "mediatophore." Proteoliposomes equipped with purified mediatophore showed a calcium-dependent activation and "fatigue" of ACh release similar to that of synaptosomes. "

1.	Acetylcholine (Acetylcholine Chloride)
2.	Complementary DNA (cDNA)
3.	Membrane Proteins (Integral Membrane Proteins)
4.	Liposomes (Liposome)
5.	Calcium
6.	proteoliposomes