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tiflucarbine
structure given in first source; calmodulin antagonist
Also Known As:
9-ethyl-4-fluoro-1-methyl-7,8,9,10-tetrahydrothieno(3,2e)pyrido(4,3b)indole lactate; TVX P 4495; TVX-P-4495
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Thiophenes: 257
tiflucarbine: 2
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Indoles: 200
tiflucarbine: 2
Organic Chemicals: 133
Sulfur Compounds: 278
Thiophenes: 257
tiflucarbine: 2
Related Diseases
1.
Psoriasis (Pustulosis Palmaris et Plantaris)
01/01/1991 - "
Therefore, we investigated the effects of the known CaM antagonist tiflucarbine (BAY/TVX P 4495) on two cellular systems related to the major clinical symptoms of psoriasis: proliferation of cultured human keratinocytes (HaCa T cell line) and release of reactive oxygen species (ROS) from human polymorphonuclear leukocytes (PMNL).
"
2.
Hypothermia
01/01/1987 - "
Tiflucarbine exerted no effect on the reserpine hypothermia, attenuated the apomorphine hypothermia and enhanced the TRH-induced hyperthermia.
"
Related Drugs and Biologics
1.
tiflucarbine
2.
Reactive Oxygen Species (Oxygen Radicals)
3.
Reserpine (Serpasil)
4.
Apomorphine
Related Therapies and Procedures
1.
Induced Hyperthermia (Thermotherapy)