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1- hexadecyl- 2- methoxyglycero- 3- phosphocholine
RN given refers to hydroxide inner salt (R)-isomer
Also Known As:
1-O-hexadecyl-2-O-methyl-rac-glycero-3-phosphocholine; 1-O-hexadecyl-2-O-methylglycero-3-phosphocholine; AMG-PC; ET-16-OCH3; ET16-OMe; HD-MO-GPC; rac-1-hexadecyl 2-methyl phosphatidylcholine
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Alcohols: 595
Sugar Alcohols: 143
Triose Sugar Alcohols: 4
Glyceryl Ethers: 12
Phospholipid Ethers: 36
1-hexadecyl-2-methoxyglycero-3-phosphocholine: 2
Ethers: 242
Glyceryl Ethers: 12
Phospholipid Ethers: 36
1-hexadecyl-2-methoxyglycero-3-phosphocholine: 2
Lipids: 114793
Membrane Lipids: 1591
Phospholipids: 11903
Glycerophosphates: 118
Phosphatidic Acids: 358
Glycerophospholipids: 689
Phospholipid Ethers: 36
1-hexadecyl-2-methoxyglycero-3-phosphocholine: 2
Related Diseases
1.
Neoplasms (Cancer)
11/01/1987 - "
The extent of AMG-PC incorporation and fluidity change was not strictly correlated with the degree to which tumor cell invasion was inhibited.
"
11/01/1987 - "
We suggest that interaction of the metabolite AMG with protein kinase C may inhibit stimulus-response coupling in tumor cells and may thus potentially contribute to the mechanism by which AMG-PC exerts its anticancer activities.
"
11/01/1987 - "
In our search for the mechanisms by which the drug 1-O-alkyl-2-O-methylglycero-3-phosphocholine (AMG-PC) inhibits tumor growth and metastasis, we have detected a metabolite, 1-O-alkyl-2-O-methylglycerol (AMG), in membranes of MO4 mouse fibrosarcoma cells grown in the presence of the drug.
"
11/01/1987 - "
Tumor cells grown in the presence of 1-O-alkyl-2-O-methylglycero-3-phosphocholine (AMG-PC) accumulated this ether lipid in their membranes.
"
2.
Neoplasm Metastasis (Metastasis)
11/01/1987 - "
In our search for the mechanisms by which the drug 1-O-alkyl-2-O-methylglycero-3-phosphocholine (AMG-PC) inhibits tumor growth and metastasis, we have detected a metabolite, 1-O-alkyl-2-O-methylglycerol (AMG), in membranes of MO4 mouse fibrosarcoma cells grown in the presence of the drug.
"
3.
Fibrosarcoma
11/01/1987 - "
In our search for the mechanisms by which the drug 1-O-alkyl-2-O-methylglycero-3-phosphocholine (AMG-PC) inhibits tumor growth and metastasis, we have detected a metabolite, 1-O-alkyl-2-O-methylglycerol (AMG), in membranes of MO4 mouse fibrosarcoma cells grown in the presence of the drug.
"
Related Drugs and Biologics
1.
Protein Kinase C
2.
Lipids
3.
Ether (Diethyl Ether)