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14-methyl-8-oxacyclorphan (BC 3016)

has high affinity for kappa-opioid receptor; structure given in first source

Also Known As:

BC 3016; BC-3016; 8-Oxamorphinan-3-ol, 17-(cyclopropylmethyl)-14-methyl-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Phenanthrenes: 27
    - Morphinans: 33
      - 14-methyl-8-oxacyclorphan: 1

Related Diseases

1.	Muscle Rigidity 02/01/1991 - "The effects of intracisternal administration of various doses (10-80 micrograms) of BC (3016) on body temperature, muscle rigidity, nociception of thermal, chemical and mechanical stimuli as well as its ability to induce catalepsy were examined. "
2.	Catalepsy 02/01/1991 - "The in vivo neurobehavioral effects of BC (3016) appear to be kappa selective since the drug did not decrease body temperature, increase muscular tone or induce catalepsy, three effects generally attributed to mu agonists. " 02/01/1991 - "The effects of intracisternal administration of various doses (10-80 micrograms) of BC (3016) on body temperature, muscle rigidity, nociception of thermal, chemical and mechanical stimuli as well as its ability to induce catalepsy were examined. " 02/01/1991 - "Furthermore, BC (3016) antagonized the immobility, trunk rigidity, catalepsy and analgesia induced by morphine. "

Related Drugs and Biologics

1.	Morphine (MS Contin)

Related Therapies and Procedures

1.	Analgesia