N- (6- phenylhexyl)- 5- chloro- 1- naphthalenesulfonamide
protein kinase C activator; RN & structure given in first source
Also Known As:
6-PHCNS; SC-9
Networked: 5
relevant articles (1 outcomes,
1 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
Related Diseases
| 1. | Stomach Neoplasms (Stomach Cancer)
11/01/1992
- " Menogaril significantly retarded the growth of 3 out of 7 stomach cancers, SC-2, SC-9 and 4-1ST, and 3 out of 4 breast cancers, H-31, MC-2 and MX-1, with overall response rates of 43 and 75% for stomach and breast cancers, respectively. " 11/01/1994
- " In addition to this study, a comparative study of SPM VIII given i.v. at 12 mg/kg/day 8 times at 3- or 4-day intervals and 5'-deoxy-5-fluorouridine (5'-DFUR) given po at 185 mg/kg/day 5 days per week for 4 weeks showed that SPM VIII had the highest effect on SC-9 human stomach cancer and COL-1 human colon cancer among the 3 compounds, resulting in a significant reduction of tumor mass. " 09/01/1993
- " Spicamycin, a nucleoside antibiotic containing fatty acids with a variety of chain lengths (C12-C18), showed potent antitumor activity against human gastric cancer SC-9 and human breast cancer MX-1 in a xenograft model. "
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| 2. | Neoplasms (Cancer)
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| 3. | Colonic Neoplasms (Colon Cancer)
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| 4. | Disease Resistance
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| 5. | Situs Inversus
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