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chounghwamycin A
produced by Streptomyces sp. No. PL-D-5
Also Known As:
Chounghwamycin A
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
3-Ring Heterocyclic Compounds
Dactinomycin: 2073
chounghwamycin A: 1
Polycyclic Compounds: 6
Macrocyclic Compounds: 15
Cyclic Peptides: 530
Dactinomycin: 2073
chounghwamycin A: 1
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
Cyclic Peptides: 530
Dactinomycin: 2073
chounghwamycin A: 1
Related Diseases
1.
Neoplasms (Cancer)
10/01/1989 - "
As more choungwamycin A is added, the mobility of the closed circular DNA increases gradually again, suggesting that the intercalation of chounghwamycin A in DNA is the primary mechanism of its action against tumor cells.
"
10/01/1989 - "
The mechanism of action of chounghwamycin A to tumor cells resembles that of actinomycin D, preferentially inhibiting the synthesis of RNA.
"
Related Drugs and Biologics
1.
RNA (Ribonucleic Acid)
2.
Circular DNA
3.
DNA (Deoxyribonucleic Acid)
4.
Dactinomycin (Actinomycin)