antisecretory factor

isolated from pituitary glands of rats, pigs, and humans, as well from the intestinal mucosa of rats and pigs; inhibits cholera-toxin induced intestinal hypersecretion; protein isolated from porcine pituitary gland had molecular weight of 60kD

Networked: 48 relevant articles (4 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Lange, Stefan: 15 articles (02/2022 - 08/2003)
2.	Jennische, Eva: 12 articles (05/2020 - 08/2003)
3.	Johansson, Ewa: 6 articles (02/2022 - 10/2003)
4.	Lange, S: 6 articles (02/2018 - 06/2000)
5.	Hansson, Hans-Arne: 5 articles (01/2020 - 08/2008)
6.	Lönnroth, Ivar: 4 articles (01/2016 - 10/2003)
7.	Jennische, E: 4 articles (04/2004 - 06/2000)
8.	Siesjö, Peter: 3 articles (04/2022 - 01/2020)
9.	Cassandro, Claudia: 3 articles (11/2020 - 01/2020)
10.	Ralli, Massimo: 3 articles (11/2020 - 01/2020)

Related Diseases

1.	Inflammation (Inflammations) 09/04/2018 - "Antisecretory factor (AF) has a role in the regulation of secretory processes and inflammation. " 02/01/2018 - "It acts by counteracting intestinal hypersecretion and various forms of inflammation, but the detailed mechanism of antisecretory factor (AF) action is unknown. " 09/01/2011 - "Antisecretory factor (AF) inhibits pathologic fluid secretion and inflammation. " 10/01/2003 - "The role of antisecretory factor in intestinal secretion and inflammation in rat." 11/01/1997 - "Antisecretory factor suppresses intestinal inflammation and hypersecretion."
2.	Wounds and Injuries (Trauma) 01/01/2020 - "Antisecretory factor, an endogenous protein, is commercially available as Salovum®, which is classified as a medical food by the European Union and has been proven effective in experimental trauma models. " 04/23/2022 - "Antisecretory factor, an endogenous protein, is commercially available as Salovum®, which is classified as a medical food by the European Union and has shown effect in experimental trauma models and feasibility with signs of effect in 2 pilot case series. "
3.	Sepsis (Septicemia) 11/24/2023 - "Antisecretory factor in breastmilk is associated with reduced incidence of sepsis in preterm infants." 11/24/2023 - "High level of antisecretory factor (AF) in mothers' own milk is associated with less risk for later sepsis in preterm infants. " 11/24/2023 - "Mother's milk containing high levels of antisecretory factor is associated with reduced risk for sepsis and inflammation in preterm infants. "
4.	Meniere Disease (Menieres Disease) 04/01/2007 - "To study the interaction among aquaporin1 (AQP), aquaporin2 (AQP2) and antisecretory factor( AF) , and their expression in the rat inner ear for furthur understanding of Meniere' s disease. " 11/01/2020 - "The role of endogenous Antisecretory Factor (AF) in the treatment of Ménière's Disease: A two-year follow-up study. " 01/01/2020 - "Food-induced stimulation of the antisecretory factor to improve symptoms in Meniere's disease: our results." 08/01/2003 - "Antisecretory factor: a clinical innovation in Ménière's disease?" 10/01/2013 - "Antisecretory factor-inducing therapy improves patient-reported functional levels in Meniere's disease."
5.	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 06/01/2000 - "Food induced stimulation of the antisecretory factor can improve symptoms in human inflammatory bowel disease: a study of a concept." 12/01/2003 - "Dietary induction of antisecretory factor (AF) can reduce diarrhoea in patients with inflammatory bowel disease. " 10/21/2014 - "Peptide AF-16, which includes the active site of Antisecretory Factor protein, has antisecretory and anti-inflammatory properties, making it a potent drug candidate for treatment of secretory and inflammatory diseases such as diarrhea, inflammatory bowel diseases, and intracranial hypertension. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Peptides (Polypeptides)
3.	peptide AF-16
4.	Therapeutic Uses
5.	Transferrin (beta 2 Transferrin)
6.	Steroids
7.	Insulin Receptor
8.	Lactoferrin
9.	Glycerol (Glycerine)
10.	Glucose (Dextrose)

Related Therapies and Procedures

1.	Therapeutics
2.	Diet Therapy (Therapy, Diet)