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hexyl nicotinate

Also Known As:

nicotinic acid hexyl ester

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Nicotinic Acids: 13
      - hexyl nicotinate: 6
- Heterocyclic Acids
  - Nicotinic Acids: 13
    - hexyl nicotinate: 6

Experts

1.	Maibach, Howard I: 1 article (07/2006)
2.	Marrakchi, Slaheddine: 1 article (07/2006)

Related Diseases

1.	Ichthyosis Vulgaris (Dominant Ichthyosis Vulgaris) 11/01/1993 - "In this study, we characterized the stratum corneum barrier function in 39 patients with various keratinization disorders (autosomal dominant ichthyosis vulgaris [ADI] [n = 7], X-linked recessive ichthyosis [XRI] [n = 6], autosomal recessive congenital ichthyosis [CI] [n = 10], dyskeratosis follicularis [Darier's disease; DD] [n = 8], erythrokeratoderma variabilis [EKV] [n = 8]), and 21 healthy volunteers, using two non-invasive methods: transepidermal water loss (TEWL) measuring outward transport of water through the skin by evaporimetry, and the vascular response to hexyl nicotinate (HN) penetration into the skin as determined by laser-Doppler flowmetry. "
2.	Darier Disease (Darier's Disease) 11/01/1993 - "In this study, we characterized the stratum corneum barrier function in 39 patients with various keratinization disorders (autosomal dominant ichthyosis vulgaris [ADI] [n = 7], X-linked recessive ichthyosis [XRI] [n = 6], autosomal recessive congenital ichthyosis [CI] [n = 10], dyskeratosis follicularis [Darier's disease; DD] [n = 8], erythrokeratoderma variabilis [EKV] [n = 8]), and 21 healthy volunteers, using two non-invasive methods: transepidermal water loss (TEWL) measuring outward transport of water through the skin by evaporimetry, and the vascular response to hexyl nicotinate (HN) penetration into the skin as determined by laser-Doppler flowmetry. "
3.	Ichthyosis (Xeroderma) 11/01/1993 - "In this study, we characterized the stratum corneum barrier function in 39 patients with various keratinization disorders (autosomal dominant ichthyosis vulgaris [ADI] [n = 7], X-linked recessive ichthyosis [XRI] [n = 6], autosomal recessive congenital ichthyosis [CI] [n = 10], dyskeratosis follicularis [Darier's disease; DD] [n = 8], erythrokeratoderma variabilis [EKV] [n = 8]), and 21 healthy volunteers, using two non-invasive methods: transepidermal water loss (TEWL) measuring outward transport of water through the skin by evaporimetry, and the vascular response to hexyl nicotinate (HN) penetration into the skin as determined by laser-Doppler flowmetry. "
4.	Erythema 10/01/1986 - "The preparations were then assessed in an in vivo experiment by measuring the time of onset of erythema induced by the hexyl nicotinate. " 01/01/1987 - "In some subjects, hexyl nicotinate may be an effective cutaneous vasodilator even in the presence of minimal erythema." 07/01/1997 - "The following tests were performed: application of 2 times the minimal irritancy dose of sodium lauryl sulfate, irradiation with 2 times the minimal erythema dose of UV-B, measurement of cutaneous vasodilation following application of ethyl and hexyl nicotinate, and reactive hyperemia following arterial occlusion. "
5.	Urticaria (Hives) 07/01/2006 - "Functional map and age-related differences in the human face: nonimmunologic contact urticaria induced by hexyl nicotinate." 07/01/2006 - "Hexyl nicotinate (HN), a lipophilic nicotinate ester, was used to induce nonimmunologic contact urticaria in human volunteers of 2 age groups: 10 young subjects [24-34 years, mean +/- standard deviation (SD) 29.8 +/- 3.9 years] and 10 older volunteers (66-83 years, mean +/- SD 73.6 +/- 17.4 years); and to define skin function and potential age-related differences in various facial areas. "

Related Drugs and Biologics

1.	Vasodilator Agents (Vasodilators)
2.	Sodium Dodecyl Sulfate (Sodium Lauryl Sulfate)
3.	Niacin (Nicotinic Acid)
4.	Minoxidil (Rogaine)
5.	Esters

Related Therapies and Procedures

1.	Lasers (Laser)