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lixazinone
structure given in first source
Also Known As:
N-cyclohexyl-N-methyl-4-(7-oxy-1,2,3,5-tetrahydroimidazo(2,1-b)quinazolin-2-one)butyramide; RS 82856; RS-82856; lixazinone sulfate; Butanamide, N-cyclohexyl-N-methyl-4-((1,2,3,5-tetrahydro-2-oxoimidazo(2,1-b)quinazolin-7-yl)oxy)-
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Quinazolines: 402
lixazinone: 3
Related Diseases
1.
Glomerulonephritis
01/01/1998 - "
Administration of lixazinone or lixazinone in combination with rolipram to rats with mesangial proliferative glomerulonephritis induced by antithymic serum suppressed proliferation of mesangial cells and also reduced other histopathologic manifestations of the disease.
"
07/15/1996 - "
We thus explored whether administration in vivo of the selective PDE-III antagonist, lixazinone (LX), together with the specific PDE-IV antagonist, rolipram (RP), can attenuate development of mesangioproliferative glomerulonephritis (MSGN) induced in rats by anti-rat thymocyte serum (ATS).
"
2.
Heart Failure
06/01/1986 - "
These data suggest that RS-82856 may be useful as an agent to increase cardiac output in the treatment of congestive heart failure.
"
Related Drugs and Biologics
1.
Rolipram