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iodofiltic acid

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labeled with 123 I for myocardial imaging; RN given refers to unlabeled, non-isomeric cpd

Also Known As:

15-(4-iodophenyl)-3-methylpentadecanoic acid; 15-(4-iodophenyl)-3-methylpentadecanoic acid, (+-)-isomer, 123I-labeled; 15-p-iodophenyl-beta-methylpentadecanoic acid; 3-methyl-4-iodophenylpentadecanoic acid; BMIPP; BMPDA; Zemiva; beta-methyl-15-(4-iodophenyl)pentadecanoic acid; iodofiltic acid I 123

Networked: 283 relevant articles (8 outcomes, 54 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Tamaki, Nagara: 13 articles (01/2016 - 12/2003)
2.	Nishimura, Masato: 10 articles (01/2016 - 08/2004)
3.	Ono, Toshihiko: 8 articles (09/2015 - 08/2004)
4.	Kikuchi, Kenjiro: 6 articles (01/2016 - 09/2003)
5.	Hashimoto, Tetsuya: 6 articles (09/2015 - 08/2004)
6.	Kobayashi, Hiroyuki: 6 articles (09/2015 - 08/2004)
7.	Hasebe, Naoyuki: 5 articles (01/2016 - 09/2003)
8.	Tamaki, N: 5 articles (06/2005 - 02/2000)
9.	Momose, Mitsuru: 4 articles (11/2015 - 10/2011)
10.	Yamazaki, Satoru: 4 articles (04/2015 - 07/2006)

Related Diseases

1.	Coronary Artery Disease (Coronary Atherosclerosis) 01/01/2016 - "In a sub-analysis of the BMIPP SPECT Analysis for Decreasing Cardiac Events in Haemodialysis Patients (B-SAFE) study, 677 asymptomatic patients with ≥1 cardiovascular risk factor and without known coronary artery disease were followed for 3years. " 02/01/2006 - "In the present study 105 consecutive patients with suspected coronary artery disease (CAD) who underwent both rest BMIPP and stress (201)Tl imaging were evaluated. " 12/01/1995 - "The purpose of this study was to evaluate iodine-123 labelled beta-methyl-branched fatty acid (BMIPP) myocardial uptake and wall motion at rest in segments with stress-induced ischaemia identified by stress 201Tl tomography in patients with chronic coronary artery disease. " 04/01/2011 - "Two meta-analyses showed this imaging technique has a diagnostic accuracy for the detection of obstructive coronary artery disease that compares favorably with SPECT myocardial perfusion imaging and that BMIPP imaging yields excellent prognostic data in patients across the spectrum of coronary artery disease. " 01/01/2010 - "We conducted a systematic review to summarize the current literature on the prognostic value of BMIPP imaging, fatty-acid metabolic imaging, for the prediction of cardiovascular events in coronary artery disease. "
2.	Myocardial Infarction 05/01/1994 - "Heart uptake and clearance of 123I-15-(p-iodophenyl)-3(R,S)-methylpentadecanoic acid (BMIPP) by whole-body scintigraphy in relation to left ventricular injection fraction (LVEF) was evaluated in 19 patients with myocardial infarction. " 04/01/2007 - "This study investigated early prediction of myocardial salvage from the T1/BMIPP mismatch and coronary flow velocity (CFV) patterns in patients with acute myocardial infarction. " 03/01/2006 - "The purpose of this study was to elucidate the relationship between the mismatch of thallium-201(Tl) and iodine-123-beta-methyl-iodophenyl-pentadecanoic acid (BMIPP) myocardial single-photon emission computed tomography (SPECT) and autonomic nervous system activity in myocardial infarction (MI) patients. " 03/01/2005 - "Prediction of functional improvement of ischemic myocardium with (123I-BMIPP SPECT and 99mTc-tetrofosmin SPECT imaging: a study of patients with large acute myocardial infarction and receiving revascularization therapy." 06/01/2004 - "Basic and clinical studies have indicated that 15-(p-[(123)I] iodophenyl)-3-(R, S) methylpentadecanoic acid (BMIPP) single photon emission computed tomography (SPECT) can identify ischemic myocardium without evidence of myocardial infarction by the regional decline of tracer uptake. "
3.	Myocardial Stunning (Stunned Myocardium) 09/01/2008 - "Stunned myocardium in transient left ventricular apical ballooning: a serial study of dual I-123 BMIPP and Tl-201 SPECT." 11/01/2009 - "LV dyssynchrony after reperfusion therapy correlates positively with Tl-BMIPP discrepancy, reflecting acute myocardial stunning, in which ventricular contraction improves during the chronic phase." 01/01/2005 - "These results indicate that increased uptake of BMIPP in stunned myocardium is mainly due to decreased beta-oxidation in tissue and increased shunt retention of BMIPP in the triglyceride pool, and thereby provide further insight into the pathophysiology of stunned myocardium." 03/01/1997 - "But there was no difference between Group 2 and 3. These findings suggested that in the segments with mismatch between BMIPP and resting perfusion reflects stunned myocardium. " 01/01/1996 - "BMIPP uptake reduction shortly after angioplasty was associated with ischemic manifestation and poor LV motion recovery, thus, it may be a sensitive representation of the stunned myocardium."
4.	Myocardial Ischemia (Ischemic Heart Diseases) 10/01/2007 - "Cardiac scintigraphy using 123I-BMIPP (123I-labeled beta-methyl-p-iodophenyl-pentadecanoic acid) showed a decreased uptake of BMIPP within the posterior wall,which improved one month later,so transient myocardial ischemia was confirmed. " 05/01/1999 - "In this study, we investigated the influence of methodological parameters on the mismatching between BMIPP and MIBI in patients with chronic ischemic heart disease. " 10/20/2014 - "The recently introduced 123I-BMIPP/201TlCl dual myocardial single-photon emission computed tomography (dual SPECT) is potentially a non-invasive diagnostic tool in detecting ischemic heart disease. " 01/01/2012 - "BMIPP SPECT when combined with CKD stage accurately predicts cardiac events among diabetic patients with suspected ischemic heart disease." 01/01/2011 - "She underwent BMIPP imaging in order to rule out ischemic heart disease. "
5.	Heart Diseases (Heart Disease) 12/01/2003 - "Several clinical studies have shown that iodine-123 labelled 15-(p-iodophenyl)-3-(R, S)-methylpentadecanoic acid (BMIPP) uptake is often lower than the uptake of perfusion tracers in patients with ischaemic heart disease. " 10/01/2001 - "In such situations, further correct information on lipid metabolism, including BMIPP, will contribute to the understanding of deteriorating heart disease and its prognosis." 08/01/1999 - "The results suggest that quantitative analysis of the uptake of sestamibi and BMIPP is a reliable method to objectively assess the presence of myocardial viability in chronic ischaemic heart disease and to predict functional improvement after revascularization." 02/01/1999 - "The incidence of a dissociation between myocardial BMIPP and 201Tl distributions (BMIPP < 201Tl) as a marker of metabolic abnormality in viable tissue varied considerably among various heart diseases. " 02/01/1999 - "I-123 labeled methyl-branched fatty acid, BMIPP, has been used mainly in Europe and Japan for the evaluation of various cardiac diseases. "

Related Drugs and Biologics

1.	pentadecanoic acid
2.	Dobutamine
3.	3-Iodobenzylguanidine (Iobenguane)
4.	Thallium
5.	Iodine
6.	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)
7.	Oxygen
8.	tranilast (N 5')
9.	Dihydrotachysterol (AT 10)
10.	Dichlorodiphenyldichloroethane (DDD)

Related Therapies and Procedures

1.	Renal Dialysis (Hemodialysis)
2.	Angioplasty (Angioplasty, Transluminal)
3.	Coronary Balloon Angioplasty (Percutaneous Transluminal Coronary Angioplasty)
4.	Drug Therapy (Chemotherapy)
5.	Thrombolytic Therapy