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EGYT 2509
binds to dopamine receptor; structure given in first source
Also Known As:
2-chloro(12-(3-dimethylaminomethyl)propyl)dibenzo(d,g)(1,3,6)dioxazocine HCl; EGYT-2509; 12H-Dibenzo(d,g)(1,3,6)dioxazocine-12-propanamine, 2-chloro-N,N,beta-trimethyl-, monohydrochloride
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
3-Ring Heterocyclic Compounds
Dibenzoxazepines: 1
EGYT 2509: 1
Related Diseases
1.
Hypotension (Low Blood Pressure)
08/01/1989 - "
The apomorphine-induced sustained hypotension was inhibited by EGYT-2509 (18.5 mg kg-1): after EGYT-2509, higher doses of apomorphine (0.7 vs 0.2 mg kg-1) were required for the effect.
"
08/01/1989 - "
Sustained hypotension could be elicited by EGYT-2509, too; after apomorphine, smaller doses of EGYT-2509 (8.5 vs 18.5 mg kg-1) were enough to decrease BP. (2) In cats anaesthetized with chloralose and urethane (50 and 400 mg kg-1 i.p., respectively), apomorphine (0.2 mg kg-1) inhibited the spontaneous activity of the postganglionic renal sympathetic nerve.(ABSTRACT TRUNCATED AT 250 WORDS)
"
Related Drugs and Biologics
1.
Urethane (Ethyl Carbamate)
2.
Chloralose
3.
Apomorphine