hemoglobin A2'

12/01/1978 - "Follow-up hematologic and family studies of presumptive beta-thalassemia gene carriers indicated that coordinate measurement of erythrocytic indices and Hb A2 values would have discriminated a subpopulation with a high incidence of beta-thalassemia trait more specifically. "
05/01/2007 - "The proband had mild microcytosis with Hb 12.9 g/dl, Hct 35.8%, MCV 74.4 fl, MCH 26.8 pg, MCHC 36.0 g/dl, and elevated Hb A2 (5.6%), characteristics of beta-thalassemia trait. "
01/01/2005 - "High Hb A2 beta-thalassemia due to a 468 bp deletion in a patient with Hb S/beta-thalassemia."
01/01/2005 - "The beta-thalassemia (thal) minor phenotypes with normal Hb A2 levels and decreased MCV and MCH values are relatively rare beta-thal traits. "
10/01/2003 - "The measurement of Hb A2 by CIEF method is rapid, precise and reproducible; it could be used in routine screening for alpha- or beta- thalassemia."

03/01/1977 - "In the latter, the highest Hb A2 levels were observed in patients with the most severe anemia. "
02/01/2001 - "Carriers were characterized by moderate anemia, hypochromia, microcytosis, elevated Hb A2 and Hb F levels, and splenomegaly. "
01/01/1988 - "Detailed gene mapping data are provided for members of a Yugoslavian and Canadian family with a thalassemia heterozygosity characterized by mild anemia with severe microcytosis and hypochromia, normal levels of Hb A2 and slightly raised Hb F levels. "
01/01/1979 - "Heterozygosity for beta-thalassemia is usually characterized by hypochromia, microcytosis, mild anemia, and increased percentage of Hb A2, and normal or mildly increased Hb F. "
03/01/1977 - "In iron-deficiency anemia, the lowest levels of Hb A2 were observed in association with the most severe anemia. "

02/01/1997 - "Efforts to increase the proportion of Hb A2 may be beneficial in sickle-cell disease."
07/01/1986 - "The sickle cell anemia patients had very high levels of Hb F and low levels of Hb A2. "
09/01/2015 - "In sickle cell disease, the quantification of Hb A2 is important for the differential diagnosis between sickle cell anemia (Hb SS) and Hb S/β(0)-thalassemia. "
04/01/2000 - "In the sickle cell syndromes, Hb A2 measurements aid in the differential diagnosis of sickle cell anemia from sickle-beta-thalassemia. "
01/01/1989 - "The variable levels of hemoglobin, MCV, Hb F, G gamma chains, and Hb A2 are in response to the heterogeneous genetic mix of the beta S-gene-cluster haplotypes and alpha-thalassemia-2 in American patients with sickle cell anemia. "

01/01/2014 - "Nine different δ chain variants and two δ-thalassemia (δ-thal) mutations were characterized in a study of 127 alleles in patients with either a low Hb A2 value or a split Hb A2 peak on high performance liquid chromatography (HPLC). "
01/01/2016 - "A variety of phenotypic expressions of hematologic features and Hb profiles were observed, including an unusual phenotype of Hb E-β0 thalassemia with 89.1% Hb E, 1.6% Hb F, and 9.3% Hb A2. "
06/01/2015 - "While in the high-prone area of β-thalassemia, MCV/MCH with Hb A2 parallel screening and MCV/MCH with Hb A2 serial screening for couples stratigies were better."
06/01/2015 - "And if the woman was β-thalassemia carrier and her husband's Hb A2 > 3.5, it meant couple positive. "
06/01/2015 - "The effect of three β-thalassemia prenatal screening strategies were compared as following: (1) MCV/MCH with Hb A2 serial screening (SS): Hb A2 was tested if the woman's MCV < 82 fl and (or) MCH < 27 pg. "

09/01/2015 - "Hb A2 levels are elevated in patients with Hb S or Hb C, and are directly influenced by the alpha thalassemia genotypes."
09/01/2015 - "However, Hb A2 values above 5.2% were seen in patients with Hb SS and Hb SC, independently of alpha thalassemia. "
09/01/2015 - "All patients homozygous for alpha thalassemia had Hb A2 levels above 3.5%. "
09/01/2015 - "The mean Hb A2 of all the Hb SC patients (n=107) was 4.01±0.507 with 4.29±0.41% and 4.91±0.22% in individuals heterozygous (n=23) and homozygous for alpha thalassemia (n=7), respectively. "
09/01/2015 - "Analysis of variance was used to compare the mean Hb A2 values between the alpha thalassemia groups. "