endodeoxyribonuclease CreI (I-CreI)

from zygotes of Chlamydomonas reinhardtii; a group I intron-encoded homing endonuclease; recognition sequence spans the cleavage site and is 24 bp in length (5'-CAAAACGTC,GTGA/GACATTTGGT)

Also Known As:

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Golic, Kent G: 1 article (04/2011)
2.	Golic, Mary M: 1 article (04/2011)
3.	Arnould, Sylvain: 1 article (08/2007)
4.	Cabaniols, Jean-Pierre: 1 article (08/2007)
5.	Duchateau, Philippe: 1 article (08/2007)
6.	Duclert, Aymeric: 1 article (08/2007)
7.	Epinat, Jean-Charles: 1 article (08/2007)
8.	Gouble, Agnès: 1 article (08/2007)
9.	Grizot, Sylvestre: 1 article (08/2007)
10.	Perez, Christophe: 1 article (08/2007)

Related Diseases

1.	Chromosome Breakage 02/22/2005 - "To resolve this issue, we compared the effects of random DNA breaks induced by X-irradiation to site-specific I-CreI endonuclease-induced chromosome breaks on cell-cycle progression in wild-type and checkpoint-defective Drosophila neuroblasts. "
2.	Xeroderma Pigmentosum (Kaposi's Disease) 08/03/2007 - "We searched the sequence of the human XPC gene, involved in the disease Xeroderma Pigmentosum (XP), for potential targets, and chose three sequences that differed from the I-CreI cleavage site over their entire length, including the central four base-pairs, whose role in the DNA/protein recognition and cleavage steps remains very elusive. "
3.	Ring Chromosomes (Ring Chromosome) 04/01/2011 - "We describe a method to construct ring-X chromosomes in Drosophila via I-CreI-mediated exchange in rDNA, and then rapidly diagnose the recovery of ring chromosomes via FLP-mediated sister chromatid exchange within the ring. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Endonucleases
3.	Ribosomal DNA (rDNA)
4.	DNA (Deoxyribonucleic Acid)