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CI 926
structure given in first source
Also Known As:
3-(4-(4-(3-methylphenyl)-1-piperazinyl)butyl)-2,4-imidazolinedione; CI-926; PD 78787; PD-78787; 2,4-Imidazolidinedione, 3-(4-(4-(3-methylphenyl)-1-piperazinyl)butyl)-
Networked:
4
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Imidazoles: 150
CI 926: 4
Related Diseases
1.
Stroke (Strokes)
06/11/2023 - "
Among 19 studies, the success rate of TRA carotid stenting was .951 (95% confidence interval [CI]: .926-.975); death rate was .022 (.011-.032); stroke rate was .005 (.001-.008); radial artery occlusion rate was .008 (.003-.013); and forearm hematoma rate was .003 (-.000 to .006).
"
2.
Hematoma
06/11/2023 - "
Among 19 studies, the success rate of TRA carotid stenting was .951 (95% confidence interval [CI]: .926-.975); death rate was .022 (.011-.032); stroke rate was .005 (.001-.008); radial artery occlusion rate was .008 (.003-.013); and forearm hematoma rate was .003 (-.000 to .006).
"
3.
Hypertension (High Blood Pressure)
08/01/1986 - "
These results demonstrate that CI-926 is a potent, orally active antihypertensive agent in renin-dependent and -independent hypertension.
"
4.
Cataract (Cataracts)
10/01/1991 - "
Cataracts in dogs following subchronic administration of the phenylpiperazine antihypertensive agent PD 78787.
"
5.
Birth Weight (Birth Weights)
11/15/1997 - "
In this group, second born infants weighed, on average, 252 g less at birth than their firstborn siblings (95% confidence interval (CI) -419 to -85), and thirdborn infants weighed 419 g less (95% CI -926 to 87), even after adjustment for trimester of maternal intrauterine exposure, maternal birth weight, smoking during pregnancy, and sex of infants in the sibling pairs.
"
Related Drugs and Biologics
1.
Antihypertensive Agents (Antihypertensives)
2.
Renin
3.
phenylpiperazine