CI 926

structure given in first source

Also Known As:

3-(4-(4-(3-methylphenyl)-1-piperazinyl)butyl)-2,4-imidazolinedione; CI-926; PD 78787; PD-78787; 2,4-Imidazolidinedione, 3-(4-(4-(3-methylphenyl)-1-piperazinyl)butyl)-

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - CI 926: 4

Related Diseases

1.	Stroke (Strokes) 06/11/2023 - "Among 19 studies, the success rate of TRA carotid stenting was .951 (95% confidence interval [CI]: .926-.975); death rate was .022 (.011-.032); stroke rate was .005 (.001-.008); radial artery occlusion rate was .008 (.003-.013); and forearm hematoma rate was .003 (-.000 to .006). "
2.	Hematoma 06/11/2023 - "Among 19 studies, the success rate of TRA carotid stenting was .951 (95% confidence interval [CI]: .926-.975); death rate was .022 (.011-.032); stroke rate was .005 (.001-.008); radial artery occlusion rate was .008 (.003-.013); and forearm hematoma rate was .003 (-.000 to .006). "
3.	Hypertension (High Blood Pressure) 08/01/1986 - "These results demonstrate that CI-926 is a potent, orally active antihypertensive agent in renin-dependent and -independent hypertension. "
4.	Cataract (Cataracts) 10/01/1991 - "Cataracts in dogs following subchronic administration of the phenylpiperazine antihypertensive agent PD 78787."
5.	Birth Weight (Birth Weights) 11/15/1997 - "In this group, second born infants weighed, on average, 252 g less at birth than their firstborn siblings (95% confidence interval (CI) -419 to -85), and thirdborn infants weighed 419 g less (95% CI -926 to 87), even after adjustment for trimester of maternal intrauterine exposure, maternal birth weight, smoking during pregnancy, and sex of infants in the sibling pairs. "

Related Drugs and Biologics

1.	Antihypertensive Agents (Antihypertensives)
2.	Renin
3.	phenylpiperazine