9-deazainosine

Networked: 4 relevant articles (2 outcomes, 0 trials/studies)

1.	Infections 01/01/1985 - "Both C-nucleosides eradicated the infection at a concentration of 0.25 micrograms/ml. Unlike formycin B, 9-deazainosine is not known to be aminated by mammalian cells and appears to be relatively nontoxic in three different mammalian tissue culture systems. "
2.	Body Weight (Weight, Body) 01/01/1987 - "The dose of orally administered 9-deazainosine calculated to suppress 50% of Leishmania donovani amastigotes in hamster livers was 19 mg/kg (body weight) per day; 96 to 99% of Leishmania organisms were eliminated from the liver and spleen of squirrel monkeys by 50 mg/kg per day. "
3.	African Trypanosomiasis (Nagana) 09/01/1987 - "Synergism between 9-deazainosine and DL-alpha-difluoromethylornithine in treatment of experimental African trypanosomiasis."
4.	Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) 06/01/1987 - "After 8 wk of immunosuppression, rats that developed severe Pneumocystis carinii pneumonia were treated with either 9-deazainosine or served as controls. " 06/01/1987 - "Pneumocystis carinii pneumonia therapy with 9-deazainosine in rats."
5.	Visceral Leishmaniasis (Kala Azar) 01/01/1987 - "Because these activities were greater than that of the experimental clinical agent allopurinol and comparable to that of the classical agent parenteral pentavalent antimony, 9-deazainosine should be considered for clinical development for visceral leishmaniasis."

1.	Therapeutics