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2- ((2- dimethylaminobenzyl)sulfinyl)benzimidazole
structure given in first source
Also Known As:
NC 1300; NC-1300; Benzenamine, 2-((1H-benzimidazol-2-ylsulfinyl)methyl)-N,N-dimethyl-
Networked:
3
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Sulfoxides: 23
2-Pyridinylmethylsulfinylbenzimidazoles
2-((2-dimethylaminobenzyl)sulfinyl)benzimidazole: 3
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyridines: 88
2-Pyridinylmethylsulfinylbenzimidazoles
2-((2-dimethylaminobenzyl)sulfinyl)benzimidazole: 3
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzimidazoles: 245
2-Pyridinylmethylsulfinylbenzimidazoles
2-((2-dimethylaminobenzyl)sulfinyl)benzimidazole: 3
Related Diseases
1.
Hemorrhagic Shock
01/28/1992 - "
In this study, the effects of proton pump inhibitors (omeprazole and NC-1300) on gastric mucosa hemodynamics and tissue oxygenation were investigated using organ reflectance spectrophotometry in a hemorrhagic shock-reperfusion model involving anesthetized rats.
"
2.
Ulcer
07/01/1989 - "
A single administration of NC-1300 to normal rats and repeated administration of NC-1300 to rats with acetic acid ulcers for four weeks after ulceration caused the same degree of inhibition of gastric acid secretion.(ABSTRACT TRUNCATED AT 250 WORDS)
"
07/01/1989 - "
Acetic acid ulcers that were healed with NC-1300 given for four weeks after ulceration remained healed for four to eight weeks after the cessation of drug administration.
"
07/01/1989 - "
Aggravation of four-week-old ulcers by indomethacin was significantly prevented by daily administration of NC-1300 (30 or 100 mg/kg) for four weeks.
"
10/01/1988 - "
The anti-ulcer effect of NC-1300, a new proton pump inhibitor, and its effect on gastric mucosal blood flow were studied in rats.
"
07/01/1989 - "
Oral administration of NC-1300 (10, 30, or 100 mg/kg) once daily for two or four weeks after ulceration dose-dependently accelerated both natural and delayed healing of acetic acid ulcers.
"
3.
Stomach Ulcer (Gastric Ulcer)
07/01/1989 - "
Effects of NC-1300 (a gastric proton pump inhibitor) on healing of experimental chronic gastric ulcers induced in rats were studied.
"
07/01/1989 - "
Effects of NC-1300, a gastric proton pump inhibitor, on healing of acetic acid-induced gastric ulcers in rats.
"
Related Drugs and Biologics
1.
Proton Pump Inhibitors
2.
Omeprazole (Prilosec)
3.
Acetic Acid (Vinegar)
4.
Indomethacin (Indometacin)
Related Therapies and Procedures
1.
Oral Administration