hypocrellin A

03/01/2019 - "Over recent decades, many studies have reported that hypocrellin A (HA) can eliminate cancer cells with proper irradiation in several cancer cell lines. "
11/01/2010 - "In vitro studies have demonstrated the active uptake of amorphous formulation of hypocrellin A into the mitochondria of tumor cells. "
03/01/2022 - "Hypocrellin A (HA), a molecule with multiple biological activities, has been shown to influence cancer growth, but the specific mechanisms of its antitumor action have not been fully explored. "
12/04/2019 - "Natural-Origin Hypocrellin-HSA Assembly for Highly Efficient NIR Light-Responsive Phototheranostics against Hypoxic Tumors."
08/01/2012 - "Hypocrellin A is an efficient photodynamic agent against many tumor cells and viruses. "

06/01/1994 - "[An experimental study on photosensitization of cultured human cells with hypocrellin A]."
07/01/1998 - "Hypocrellin A photosensitization involves an intracellular pH decrease in 3T3 cells."
06/01/1994 - "All the aforesaid results indicated that photosensitization of hypocrellin A inhibits cells growth, resulting from the damage in cell membrane and cytoskeleton and S phase delay of the cell cycle."
02/01/1992 - "DNA damage induced by hypocrellin-A photosensitization."
09/01/1989 - "The primary reaction of photosensitization of Hypocrellin A (HA) has been studied by using techniques of ESR, spin-trapping and spin-counteraction. "

09/01/2001 - "In this study, we have examined the photodynamic effects of Hypocrellin A and B compounds in poorly differentiated (CNE2) and moderately differentiated (TW0-1) human nasopharyngeal carcinoma (NPC) cells. "
03/01/2002 - "Human poorly (CNE2) and moderately differentiated (TW0-1) human nasopharyngeal carcinoma (NPC) cells undergo rapid apoptosis when treated with PDT sensitized with Hypocrellin A (HA) and Hypocrellin B (HB). "

04/01/1996 - "It appears that oxyradicals, generated during the photodynamic process, may be associated with the treatment of various skin diseases by photodynamic therapy of Hypocrellin A."
09/14/2019 - "and its major active substance hypocrellin exert unique curative effects on skin diseases, diabetes, and cancers. "
01/01/2019 - "Hypocrellin A (HA) is a natural red perylenequinone pigment from Shiraia fruiting body, which was used clinically on various skin diseases and developed as a photodynamic therapy agent against cancers. "
06/01/2016 - "Hypocrellin A (HA), well known as one of the best natural pigments and bioactive agent to treat skin diseases, is further anticipated to play a vital role in photodynamic therapy (PDT) in anticancer and antiviral treatments. "
05/01/2018 - "Hypocrellin A (HA) is a major bioactive perylenequinone from the fruiting body of Shiraia bambusicola used for the treatment of skin diseases and developed as a photodynamic therapy (PDT) agent against cancers and viruses. "

05/03/2010 - "Toxicity and phototoxicity of Hypocrellin A on malignant human cell lines, evidence of a synergistic action of photodynamic therapy with Imatinib mesylate."
12/01/2000 - "Hypocrellin and hypericin-induced phototoxicity of HL-60 cells: apoptosis or necrosis?"
11/01/1999 - "Potentiation of hypericin and hypocrellin-induced phototoxicity by omeprazole."
12/01/2002 - "Hypocrellin compounds were selected as potential photosensitizers for PDT owing to their high quantum yields of singlet oxygen (1O2), and facility for site-directed chemical modification to enhance phototoxicity, pharmacokinetics, solubility, and light absorption in the red spectral region, among other properties. "
01/01/1996 - "Hypocrellin compounds were selected as potential photosensitizers for photodynamic therapy (PDT) owing to their high quantum yields of singlet oxygen (1O2), and facility for site-directed chemical modification to enhance phototoxicity, pharmacokinetics, solubility, and light absorption in the red spectral region, among other properties. "