juliflorine

alkaloid from Psosopis juliflora; structure given in first source

Also Known As:

juliprosopin; juliprosopine; 3-Piperidinol, 6,6'-((1,2,3,5,8,8a-hexahydro-6,8-indolizinediyl)di-10,1-decanediyl)bis(2-methyl)

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Chang, Fang Rong: 1 article (01/2017)
2.	Dahms, Hans-Uwe: 1 article (01/2017)
3.	Henciya, Santhaseelan: 1 article (01/2017)
4.	James, Arthur Rathinam: 1 article (01/2017)
5.	Nikam, Rahul: 1 article (01/2017)
6.	Seturaman, Prabha: 1 article (01/2017)
7.	Tsai, Yi-Hong: 1 article (01/2017)
8.	Wu, Yang-Chang: 1 article (01/2017)
9.	Ahmad, Viqar Uddin: 1 article (07/2005)
10.	Ahmed, Amir: 1 article (07/2005)

1.	Alzheimer Disease (Alzheimer's Disease) 07/15/2005 - "Juliflorine: a potent natural peripheral anionic-site-binding inhibitor of acetylcholinesterase with calcium-channel blocking potential, a leading candidate for Alzheimer's disease therapy." 01/01/2017 - "The compound juliflorine provides a cure in Alzheimer disease by inhibiting acetylcholine esterase at cholinergic brain synapses. "
2.	Lethargy 02/01/1991 - "In vero cell-line juliflorine was found toxic at greater than or equal to 5 micrograms/ml. Injected animals showed lethargy, prostration and weakness (dose dependent) but recovered after some days, while newly hatched chicks, from injected eggs with higher dose, did not survive after 48 to 72 h. "
3.	Inflammation (Inflammations) 02/01/1991 - "Topically 1% juliflorine in polyethylene glycol-400 was found non-toxic but higher concentrations (less than or equal to 2.5%) produced irritation and inflammation; the severity of reaction was dose dependent. "

1.	Polyethylene (Polythene)
2.	Cholinergic Agents (Cholinergics)
3.	Calcium Channels (Calcium Channel)
4.	Esterases
5.	Acetylcholinesterase
6.	Acetylcholine (Acetylcholine Chloride)

1.	Therapeutics