himbacine

08/08/2001 - "This study examined whether the M(4)-selective antagonist, himbacine, could also prevent myopia. "
08/08/2001 - "Findings demonstrate himbacine is effective at preventing the development of myopia in chick and implicates a role for the M4 receptor."
08/08/2001 - "Inhibition of myopia development in chicks using himbacine: a role for M(4) receptors?"
08/08/2001 - "Daily intravitreal injections of himbacine inhibited the inducement of myopia in chick eyes in a dose- dependent manner. "
03/01/2003 - "Atropine, pirenzepine, and himbacine prevent form-deprivation myopia (FDM) when administered intravitreously. "

11/01/2014 - "Vorapaxar is a non-peptide himbacine analogue that has been developed for the reduction of thrombotic cardiovascular events in patients with a history of myocardial infarction or peripheral arterial disease. "

01/01/1994 - "The affinity of himbacine for the vas deferens site (pA2 8.08) was nearly ten times higher than those for the M1 receptors of rat ganglion and dog saphenous vein (pA2 7.14 and 7.16, respectively); affinity estimates for pirenzepine were similar throughout the different preparations. "

04/01/1991 - "Both side-effect profiles and the ability to reverse MPTP-induced hypokinesia were assessed using a variety of dopamine receptor agonists (quinpirole, PHNO, ADTN), cholinergic antagonists (scopolamine, secoverine, himbacine), a glutamate receptor antagonist (MK801) and a 5-HT receptor agonist (8-OH-DPAT). "

11/01/1992 - "Himbacine was a potent blocker of oxotremorine-M-mediated cyclic AMP inhibition in rat striatum (4.4 nM) and in N1E-115 neuroblastoma cells (10.6 nM), responses mediated by M4 receptors. "